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What is Duloxetine?
Duloxetine is used for the treatment of depression and anxiety. It is also used to help relieve nerve pain in diabetic individuals or ongoing pain due to medical conditions such as chronic back pain, arthritis, or fibromyalgia.
Duloxetine may improve your mood, appetite, and energy level. It may also decrease nervousness and help decrease pain due to certain medical conditions.
Duloxetine belongs to the class of medications known as selective serotonin and norepinephrine reuptake inhibitors or SNRIs.
How does Duloxetine work?
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor. It works by increasing the levels of serotonin and norepinephrine, which are substances that naturally occur in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
What are the benefits of using Duloxetine?
The main benefit of Duloxetine is the increase in the amount of serotonin and norepinephrine in the brain to help maintain mental balance and stop the movement of pain signals in the brain.
How do I use Duloxetine?
Strictly follow the instructions of your doctor on how to properly use this medication. It will help also that before you start taking this medication you should read the Patient Information Leaflet that comes with the medication package when you fill up your prescription.
Take Duloxetine as directed. Do not take more or less of the medicine, take it more often than instructed by your doctor, or take it for longer than what is prescribed by your doctor.
Duloxetine comes as a delayed-release capsule to be taken by mouth. When taken for the treatment of depression, Duloxetine is usually taken once or twice daily with or without a meal. When it is taken to treat generalized anxiety disorder, fibromyalgia, the pain of diabetic neuropathy, or ongoing bone or muscle pain, it is usually taken once a day with or without a meal.
Swallow the delayed-release capsule whole, without splitting, chewing, or crushing them. Do not open the delayed-release capsules and mix the contents with liquids or sprinkle the contents on food.
Your doctor may start you on a low dose of Duloxetine and increase your dose after one week.
This medication may help you control your symptoms but will not cure the condition. It may take 1 to 4 weeks or longer before you feel the full benefits of this medication. Continue taking the medication even if you feel well. Do not stop taking the medication without first getting the approval of your doctor. Your doctor will decrease your dose gradually. You may experience withdrawal symptoms when you suddenly stop taking this medication.
For the treatment of depression - The usual dose is one or two capsules once daily.
For generalized anxiety, fibromyalgia, the pain of diabetic neuropathy, or ongoing bone or muscle pain - The usual dose is one capsule once daily.
Side effects & precautions
Your doctor has prescribed this medication because he deemed that the benefits outweigh the risks of side effects although not everyone who uses this medication experiences the side effects.
The following are the common side effects of Duloxetine:
- Dry mouth
- Loss of appetite
- Increased sweating
If any of these side effects persist or worsen, report to your doctor immediately.
Lightheadedness or dizziness may occur, especially when you first start or increase your dose of this drug. To reduce the risk of lightheadedness, dizziness, or falling, it is recommended that you get up slowly when rising from a lying or sitting position.
Duloxetine may raise your blood pressure. Check your blood pressure regularly and report to your doctor if the results are high.
Immediately report to your doctor if you experience any of the serious side effects:
- Decreased interest in sex
- Easy bruising or bleeding
- Changes in sexual ability
- Signs of liver problems
- Muscle cramps or weakness
Seek immediate medical help if you have any of the very serious side effects such as:
- Black or bloody stools
- Vomit that looks like coffee grounds
- Widened pupils
- Vision changes
- Swelling or redness of the eyes
Duloxetine may raise your level of serotonin and cause a very serious condition called serotonin syndrome. Your risk for this condition will increase if you are also taking drugs that increase serotonin. Get medical help if you develop the following symptoms:
- Fast heartbeat
- Severe dizziness
- Loss of coordination
- Severe nausea or vomiting
- Unexplained fever
- Twitching muscles
- Unusual agitation
A serious allergic reaction to Duloxetine is rare. Get immediate medical help if you notice any symptoms of a serious allergic reaction, including:
- Severe dizziness
- Itching or swelling of the face, tongue, or throat
- Mouth sores
- Skin blisters
Report to your doctor if you experience any other side effects that are associated with your use of Duloxetine.
Before you start taking this medication, let your doctor know if you are allergic to it, or if you have other allergies. Duloxetine may have some inactive ingredients that can trigger an allergic reaction or other problems.
Share with your doctor your medical history before taking this medication, especially of family history of psychiatric disorders, history of suicide attempts, family history of glaucoma, kidney disease, high blood pressure, liver disease, stomach problems, or seizure disorder.
Duloxetine may make you drowsy or dizzy. Alcohol consumption and marijuana use may make you drowsier or dizzier. Do not perform any activity that requires alertness until you are sure that you can do it safely. Avoid consuming alcoholic beverages. Discuss with your doctor your marijuana use
This medication may affect your blood sugar if you are diabetic. Check your blood sugar regularly and share the results with your doctor. Your doctor may have to adjust your medication, diet, and exercise program.
Older adults may be more sensitive to the side effects of Duloxetine, especially lightheadedness, bleeding, or loss of coordination, conditions that can increase the risk of falling.
Children may be more sensitive to the side effects of this drug, especially weight loss and loss of appetite. Monitor weight and height in children who are taking this medication.
This medication should be used in pregnancy only when clearly needed. Babies born to mothers who used this medication during the last trimester of pregnancy may develop withdrawal symptoms such as seizures, difficulty in feeding or breathing, constant crying, or muscle stiffness.
Duloxetine passes into breast milk and may have undesirable effects on a nursing infant. Consult first your doctor before you decide to breastfeed.
Drug interactions may alter the way your medications work or increase the risk of side effects. Share with your doctor a list of all medications you are currently taking before you start taking this medication. Get first the approval of your doctor before you start, top, or change the dosage of any medicine.
Some drugs may interact with Duloxetine such as drugs that can cause bleeding or bruising - NSAIDs, and blood thinners.
How do I buy Duloxetine online?
You can safely buy Duloxetine online at UK Meds. You will first need to have an online consultation with a pharmacist independent prescriber before your order will be supplied. The online consultation will ensure that Duloxetine is the right medication for your medical condition.
Duloxetine is but one type of anxiety medicine. There are other types your doctor may decide is more appropriate for the treatment of anxiety, such as Propranolol anxiety medicine. Your doctor will select the best medication for your diagnosis.