Promethazine / Promethazine Hydrochloride


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Promethazine (Promethazine Hydrochloride) is used to treat the symptoms of an allergic reaction such as itching, rash, and runny nose and nausea.

  • Treats itching, sneezing and runny nose
  • Provides relief from seasonal allergies
  • Long lasting
  • Genuine medication
  • All drugs sourced in the UK
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More Information

Type of drugAntihistamines
Health conditions prescribed forhay fever, allergies, insomnia, hives, nausea, vomiting, vertigo, motion sickness
Active ingredientPromethazine hydrochloride
Brand nameAvomine, Phenergan, Sominex, Vertigon
Available strength10mg, 25mg
Available asTablets, oral liquid, injections
Possible side effectsConstipation, stomach upset, headaches, dizziness, dry mouth, difficulty passing urine, sleepiness, blurred vision

Promethazine Hydrochloride

Promethazine is a medicine for the prevention and treatment of vomiting and nausea related to certain conditions such as motion sickness, or before and after surgery. The active ingredient in promethazine tablets is Promethazine Hydrochloride. This medicine is also used to treat the symptoms of an allergic reaction such as itching, rash, and runny nose.

Promethazine may be used to help you feel relaxed or sleepy before or after surgery or to help some narcotic pain relievers such as meperidine work better.

There is a suppository form of this medication when the regular tablet cannot be taken by mouth.

Promethazine is an antihistaminic available under the brand names Sominex, Phenadoz and Phenergan.

For more information on the prescription medication patients should refer to the Promethazine / Promethazine Hydrochloride patient information leaflet.

Promethazine is an antihistaminic. It works by blocking histamine that your body produces during an allergic reaction. Its other effects - anti-nausea, pain relief, or calming - may affect some natural substances such as acetylcholine and by acting directly on certain parts of the brain.

The main benefit of using Promethazine is the prevention and relief that it provides to vomiting and nausea related to motion sickness, or before and after surgery. This medicine is also an effective treatment for the symptoms of an allergic reaction.

Promethazine Tablets

Take this medication exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may change your dose of this medication to make sure that you get the most benefits from it. Do not take Promethazine in larger or smaller amounts or for longer than recommended by your doctor.

Promethazine is best taken at bedtime or before meals. Take this medicine within 1 hour before travelling to prevent motion sickness. When this medicine is used for surgery, it is usually taken the night before the surgery.

The frequency and timing of your dose will depend on the condition being treated.

When using the liquid form of this medicine, measure the liquid with the dosing syringe that is provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, your pharmacist can give you one.

When administered to a child, tell your doctor if the child has any changes in weight because the doses of this medicine are based on the body weight of the children. Any changes in weight may affect the child’s dose.

Inform your doctor if the symptoms do not improve, or if they get worse while using this medication.

Promethazine is available in the following forms and strengths:

  • Tablet - 12.5 mg, 25 mg, and 50 mg.
  • Suppository - 12.5 mg, 25 mg, and 50 mg
  • Injectable solution - 25 mg/ml and 50 mg/ml
  • Syrup - 6.25 mg/5ml

Promethazine should be given as follows:

For allergy:

  • Taken orally or rectally: 25 mg at bedtime or 12.5 mg before meals and at bedtime
  • Intravenously or intramuscularly: 15 mg. May be repeated in 2 hours as needed. Switch to oral dosing as soon as possible.

Buy Promethazine

Promethazine Boots

At the time of writing, Promethazine is not available at Boots. However, should you wish to purchase Promethazine, you can do so at UK Meds.

You can safely buy Promethazine online at UK Meds. You will first need to have an online consultation with a pharmacist independent prescriber before your order will be supplied. The online consultation will ensure that Promethazine is the right medication for your medical condition.


Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled content writer dedicated to creating helpful and accessible medical content for UK Meds.

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