Nexium Control

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Nexium Control tablets provide a highly effective, daily treatment for frequent heartburn and acid reflux. Each tablet contains 20mg of esomeprazole, which belongs to a group of medicines known as proton pump inhibitors (PPIs). They work directly at the source by safely blocking the specific pumps in your stomach that produce excess acid.

While this medication provides lasting 24-hour protection, it does not provide instant relief. You may need to take Nexium Control consecutively for 2 to 3 days before you notice the full effects of the treatment.

Looking for the generic form? Esomeprazole is also available to safely purchase at UK Meds.

  • Clinically proven to treat heartburn and acid reflux
  • Blocks stomach acid for up to 24 hours
  • Easy dosage of just one tablet per day
  • Genuine, UK-sourced over-the-counter medication
  • Fast, tracked delivery directly to your door
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More information

Nexium Control tablets are a daily over-the-counter medication designed to reduce the amount of acid your stomach produces, effectively relieving symptoms of acid reflux and heartburn. By safely turning down gastric acid production, these tablets soothe the burning sensation in your chest and throat, allowing you to comfortably go about your day without painful acid irritation.

Nexium Control works by utilizing its active ingredient, esomeprazole, which belongs to a highly effective group of medicines called proton pump inhibitors (PPIs)[1]. These tablets work by directly blocking the specific 'proton pumps' in your stomach lining that are responsible for secreting acid. Because the medication needs to shut down these pumps, it does not provide instant relief; you may need to take Nexium Control tablets consecutively for 2 to 3 days before you notice the full effects and experience maximum symptom relief.

The primary benefit of taking Nexium Control is the reliable, long-lasting prevention of excess stomach acid, which quickly relieves the pain of acid reflux and heartburn. A number of uncomfortable problems can occur when excess stomach acid irritates your oesophagus and digestive system. Crucially, this reduction in acid gives your digestive system the necessary time it needs to heal from inflammation and irritation[2].

Usage & Dosage Advice

To use Nexium Control tablets correctly, you should swallow one whole with a drink of water, either with or without food. Always follow the guidance given in the enclosed patient information leaflet and be sure to read it before commencing your first dose. You must not chew, crush, or break the tablet before swallowing, as this destroys the protective coating and prevents the medicine from working properly.

The recommended dose of Nexium Control is one 20mg tablet per day[3]. You should never exceed this daily dose, even if you don’t feel the effects of the medication straight away, as it can take 2 to 3 days for the active ingredients to take full effect.

ScenarioRecommended Action
Standard Daily DoseTake 1 tablet (20mg) per day with water.
If you forget a doseTake it as soon as you remember on the same day. If it’s nearly time for your next dose, skip the forgotten one and take the next dose as normal. Do not double up to make up for a missed dose.
If you take too muchContact a doctor immediately. You may experience overdose side effects such as severe diarrhoea, stomach ache, or nausea.

Side Effects & Precautions

Like with all medicines, there is a small risk of side effects when using Nexium Control. You should cease using the medication immediately and contact your doctor if you experience any serious side effects or if you notice signs of an allergic reaction (such as swelling of the face, lips, or throat).

Common side effects include:

  • Headaches
  • Effects on your stomach or gut: diarrhoea, stomach ache, constipation, or wind (flatulence)
  • Feeling sick (nausea) or being sick (vomiting)
  • Benign growths (polyps) in the stomach

You should avoid taking Nexium Control tablets if you are allergic to esomeprazole or any of the other active ingredients. Before taking this medication, you should always check that it is suitable for your medical profile. Do not take this treatment if:

  • You are allergic to medicines containing other proton pump inhibitors (e.g., pantoprazole, lansoprazole, rabeprazole, or omeprazole)
  • You are taking a medicine containing nelfinavir (used to treat HIV infections)
  • You are currently breastfeeding

You must consult a doctor before taking Nexium Control if any of the following apply:

  • You have a history of stomach ulcers or stomach surgery
  • You have been taking continuous treatment for reflux or heartburn for 4 or more weeks
  • You have jaundice (yellowing of skin or eyes) or severe liver/kidney problems
  • You are aged over 55 and have new or recently changed reflux symptoms, or need to take daily indigestion remedies
  • You have ever had a skin reaction after using a similar acid-reducing medicine
  • You are due to have an endoscopy, a urea breath test, or a Chromogranin A blood test

Because of the way esomeprazole alters stomach acid, it can affect how your body absorbs other drugs. You should be cautious and consult with a doctor or pharmacist if you are currently taking any of the following medicines[4]:

Condition TreatedInteracting Medicines to Check
Fungal or Bacterial InfectionsKetoconazole, itraconazole, voriconazole, or clarithromycin
Depression & AnxietyCitalopram, imipramine, clomipramine, diazepam, or St. John’s wort
Heart Problems & BloodDigoxin, cilostazol, or blood thinners (e.g., warfarin)
HIV InfectionsAtazanavir, saquinavir, or nelfinavir (Do not use with nelfinavir)
Cancer & Immune SystemErlotinib, methotrexate, or tacrolimus (organ transplants)
Epilepsy & OtherPhenytoin, rifampicin (tuberculosis), or cisapride (indigestion)

Hearing from others who suffer from frequent heartburn can help you understand what to expect. Swipe through these patient experience videos to see how Nexium Control tablets have helped people protect their digestive systems and get back to enjoying their everyday lives without the disruption of acid reflux.

Swipe left or right to view more videos

Can I drink alcohol while taking Nexium Control tablets?

While alcohol does not directly interact with the active ingredient (esomeprazole), drinking alcohol relaxes the valve at the top of your stomach and irritates the stomach lining. This can actively worsen your acid reflux symptoms, counteracting the healing benefits of the medication.

What is the difference between Nexium Control and Omeprazole?

Both are highly effective proton pump inhibitors (PPIs) used to treat excess stomach acid. Nexium Control contains esomeprazole, which is a slightly refined, mirror-image molecule of omeprazole. While they work in the exact same way, some patients find that one simply works better or faster for their specific body chemistry.

Can I take Nexium Control with painkillers like ibuprofen?

It is perfectly safe to take everyday painkillers like paracetamol alongside this medication. However, you should generally avoid taking non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin, as these are known to irritate the stomach lining and can trigger heartburn.

Is it safe to use this medication while pregnant?

As a general safety precaution, you should avoid taking Nexium Control during pregnancy or while breastfeeding. If you are suffering from severe pregnancy-induced heartburn, you should speak to your doctor or midwife, who can prescribe a pregnancy-safe alternative.

You can safely buy Nexium Control tablets online at UK Meds, without the need for a prior prescription or consultation with a medical professional. However, you should always adhere to the safety advice given in the patient leaflet enclosed. Simply add the medication to your basket and complete your secure order for fast, tracked delivery straight to your door.

If you want to learn more about staying comfortable and protecting your digestion, we have put together some simple guides for you. These easy-to-read articles will help you understand your tummy and how to manage your symptoms:

  • How can I treat heartburn?

    Learn about the best ways to stop the burning feeling in your chest and make your tummy feel better quickly.

  • How to treat acid reflux

    Find out exactly how to calm down acid reflux so you can eat your favourite foods without any pain or sick feelings.

  • How do you avoid acid reflux?

    Discover simple, everyday tips and tricks to stop stomach acid from coming up into your throat in the first place.

Clinical Sources & References

To make sure all the medical information on this page is perfectly safe and correct, we used the following trusted UK health experts:

  1. NHS: Esomeprazole Health Information
  2. Patient.info: Esomeprazole to Reduce Stomach Acid
  3. BNF NICE: Esomeprazole Prescribing Guidelines
  4. EMC: Nexium Control Summary of Product Characteristics

Our Commitment to Content Accuracy

UK Meds is committed to providing clear, accurate and up-to-date medical information in line with our Editorial Policy and Content Policy. All content is regularly reviewed to help you make informed decisions before purchasing your over-the-counter medication.

Medical Disclaimer: The information on this page is not a substitute for medical advice. Always read the patient information leaflet and speak to a doctor or pharmacist before beginning any treatment.

Page Last Updated: 17th April 2026

Author

Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled medical content writer dedicated to creating helpful and accessible health and wellbeing content for UK Meds.

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