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Ibuprofen belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It is used to ease mild to moderate pain such as toothache, migraines and period pain. Also, it can reduce high temperatures, ease pain and swelling caused by sprains and strains, and reduce the pain and inflammation caused by arthritis and other conditions.

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Arthritis Pain

UK Meds asked our favorite doctor, Dr. Christian Jessen, to explain Arthritis. Below is what he has to say.

Arthritis simply means the inflammation of joints. Under normal circumstances, inflammation is part of the body's healing process. It happens naturally when fighting off infections or healing a wound. The inflammation associated with rheumatoid arthritis, however, occurs because your immune system mistakingly attacks and damages your joints causing pain and stiffness. The inflammation can also affect the ligaments and tendons which surround the joints, and is known as an auto-immune disease.

Around 350 million men and women worldwide suffer from some form of arthritis. There are medicines which can help control it, including Ibuprofen, Celebrex, Naproxen, Ponstan and others. They work to counteract the inflammation and so reduce the joint damage. If you are suffering from arthritis and you would like to purchase arthritis medication, you can start with a free online consultation ok the UK Meds website for your prescription from GMC registered doctors.

- Dr. Christian Jessen

The video and article above is for information purposes only. They are not intended to diagnose a condition or prescribe a medicine. If you have any specific concerns about your health, please consult your GP or use our online doctor's service. You can follow Dr. Christian Jessen online on his Twitter account.

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What is Ibuprofen?

Ibuprofen is used to relieve pain from various conditions such as headache, dental pain, menstrual cramps, muscle aches, or arthritis. It is also used to reduce fever and to relieve minor aches and pain due to the common cold or flu. It is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation. This effect helps to decrease swelling, pain, or fever.

If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.


  • Ibuprofen, sold under the brand names Advil, Motrin, and Ibuprin, is a medication used to relieve pain, swelling and inflammation.
  • Motrin and Advil can be purchased over-the-counter in 200 milligram (mg) tablets, while higher doses require a prescription.
  • Available in tablets and capsules, it is also found in combination with other drugs sold over-the-counter (OTC) for cough, cold, and migraine.
  • In certain situations, it may be given in hospitals in liquid form through the veins, or intravenously (IV).
  • It belongs to group of drugs known as non-steroidal anti-inflammatory drugs, or NSAIDs, which work by inhibiting prostaglandins, chemicals that can cause inflammation in the body.
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Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.

Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. About 60% of people improve with any given NSAID, and it is recommended that if one does not work then another should be tried. It may also be used to close a patent ductus arteriosus in a premature baby. It can be used by mouth or intravenously. It typically begins working within an hour. You can buy it online from UK Meds.

Ibuprofen belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Other members of this class include aspirin, naproxen (Aleve), indomethacin (Indocin), nabumetone (Relafen) and several others. These drugs are used for the management of mild to moderate pain, fever, and inflammation. Pain, fever, and inflammation are promoted by the release in the body of chemicals called prostaglandins. It blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower levels of prostaglandins. As a consequence, inflammation, pain and fever are reduced.

Side Effects

Ibuprofen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using ibuprofen, especially in older adults.

Ibuprofen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine. Ibuprofen is an NSAID, a type of medication with analgesic, fever-reducing, and, in higher doses, anti-inflammatory effects.

Pregnancy and Ibuprofen

  • Because the risk of harm to an unborn child varies during pregnancy, this medicine falls under two pregnancy categories:
  • For the first 29 weeks of pregnancy, it carries some risk of harm to the fetus.
  • For women who are 30 weeks and beyond, it should only be taken in situations when there are no safer options available.
  • It can cause a birth defect by causing a major artery that nourishes the baby's heart to close too soon.
  • It is also found in breast milk, and mothers should avoid taking this drug while breastfeeding.
  • Regardless, you should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.
  • You should also alert your physician if you are breastfeeding or plan to breastfeed.

The World Health Organization (WHO) includes ibuprofen in a list of the minimum medical needs for a basic healthcare system known as its "Essential Drugs List." A non-steroidal drug is not a steroid. Steroids often have similar effects, but long-term use can cause severe adverse effects. Most NSAIDs are non-narcotic, so they do not cause insensibility or stupor.

The original brand name made by Boots was Brufen but it is now made by a number of manufacturers as the patent has expired.

It works by acting on a group of compounds called prostaglandins. Prostaglandins are sometimes called local hormones because they act close to where they are produced rather than all over the body. They have a remarkably wide range of effects. One of their actions is to cause inflammation.

When a part of the body is injured, protective mechanisms go into action. White blood cells accumulate at the site of the injury, and this causes swelling, heat, redness, loss of function, fever and pain - together called inflammation.

All these effects are potentially beneficial. Swelling can help to immobilise (keep still) injured joints, heat and increased blood flow promote healing and pain alerts the injured person that there is a problem. However, they can often be too much of a good thing - once we know we are injured, the pain no longer has a function and we wish to be rid if it. Often we find that the inflammatory response is too powerful and can do more harm than good.

Ibuprofen’s action as a painkiller and antipyretic (fever-reducing) compound is due to its ability to inhibit the synthesis of prostaglandins. It does this by interfering with the action of an enzyme called cyclo-oxygenase (COX) which catalyses (speeds up) the conversion of a compound called arachidonic acid into prostaglandins. Aspirin and other NSAIDs work in a similar way.