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Pioglitazone is a medication belonging to the class of thiazolidinediones, which is used to treat type 2 diabetes. It contains the active ingredient pioglitazone hydrochloride, which helps to improve insulin sensitivity and regulate blood sugar levels. Pioglitazone is also branded as Actos.

  • Suitable for adults
  • Makes better use of insulin
  • Treats type 2 diabetes
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You will need to answer a few questions about your health before completing purchase of this item.

Pioglitazone is a medication that is used to help treat type 2 diabetes. This is a condition that means that the body does not make enough insulin, resulting in high blood sugar levels.


Pioglitazone is also available in branded form as Actos.

Pioglitazone contains the active ingredient Pioglitazone hydrochloride. This medication works by helping your body to make better use of the insulin that it produces. 

You can use Pioglitazone at any time during the day whether it is in the morning or the evening. You should however try and take your medication at the same time every day. This medication can be taken with water, and with or without food.

You should only ever use the dosage of Pioglitazone that you have been told to use by your healthcare provider. The usual starting dose is one tablet taken once a day. The maximum daily  dosage of Pioglitazone is 45mg.

The majority of adults over the age of 18 years old can use Pioglitazone to help treat their type 2 diabetes.

Pioglitazone may not be a suitable medication for some people. This medication should not be used by anyone who is allergic to any of the ingredients in it. It should also not be used by anyone under the age of 18. Do not use Pioglitazone if:

  • You have liver or heart problems
  • You have ever had blood in your urine
  • You have ever had bladder cancer
  • You have a condition that affects your bones such as osteoporosis
  • You have a health condition caused by diabetes

No, you should not use Pioglitazone whilst you are pregnant as there is limited knowledge about its safety. There are other medications that can be used during pregnancy, such as Metformin, which your doctor will prescribe you over Pioglitazone.

No, it is not usually recommended to use Pioglitazone whilst you are breastfeeding. Your doctor may provide you with another medication. If they think it is suitable for you, you should contact your doctor or midwife as soon as possible if:

  • Your baby is not feeding as well as they used to
  • They seem irritable or sleepier than normal
  • They are paler or sweatier than normal
  • They are urinating more

Pioglitazone may interact with other medications. It is important to let your healthcare provider know about any medications you are taking, or have taken in the past. Tell your doctor if:

  • You are using gemfibrozil, a medication used to reduce cholesterol
  • You are using rifampicin, an antibiotic used to treat tuberculosis

As with all other medications, some users may experience side effects when they are using Pioglitazone. Some of the most common side effects include:

  • Sinus, throat or chest infections
  • Issues with the eyes
  • Weight gain
  • Pins and needles
  • Numb fingers or toes

To understand all of the warnings associated with Pioglitazone it is important that you fully read the patient information leaflet that is provided with your medication.

Buy Pioglitazone

You can purchase Pioglitazone online from UK Meds which will be delivered straight to your door.

The medication is also available in its branded form of Actos.


Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled content writer dedicated to creating helpful and accessible medical content for UK Meds.

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