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  • Effective antibiotic
  • Kills the bacteria that causes UTI's
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Trimethoprim is an antibiotic to treat bacterial infections. It is suitable for the treatment of acute urinary and other bacterial infections. It is a not a treatment for viral infections such as the common cold and flu.

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Please note: this page is only to be used as a reference of our price for this medication. If you are approved for Women’s Health medication, you will be offered treatment for you and the prescriber to jointly consider. However, the final decision will always be the prescriber's.

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Read up

    Trimethoprim is an antibiotic to treat bacterial infections. It is suitable for the treatment of acute urinary and other bacterial infections. It is a not a treatment for viral infections like the common cold and flu. The effectiveness of trimethoprim and other antibiotics will be decrease when used unnecessarily or when overused.

    Trimethoprim is an antibiotic. It is used to treat infections with bacteria.

    Bacterial grow and multiply by producing genetic materials for the cells. The bacteria need folic acid to grow the genetic material. Unlike humans that take up folic acid from the diet, bacteria synthesize folic acid themselves. Trimethoprim works by stopping the folate production by the bacteria. With no folate produced, the bacteria will not be able to produce the genetic material necessary for their growth and multiplication. By preventing the bacteria from producing folate, trimethoprim stops the spread of infection in the human body. The remaining bacteria will eventually die or are killed by the immune system.

    The doctor should make sure that the bacteria causing the infection are susceptible to trimethoprim before prescribing the medication. The doctor may take a tissue sample from the infected area and the bacteria present in the sample will be cultured and examined later for identification.

    When administered to a patient with an infection caused by bacteria that are susceptible to trimethoprim, the bacteria will be deprived of their ability to produce folic acid, which the bacteria will synthesize to produce the genetic material necessary for growth and multiplication.

    Trimethoprim stops the growth and multiplication of the bacteria, arresting the infection.

    Doctors must make sure that the bacteria causing the infection are susceptible to trimethoprim, otherwise the infection will not be treated.

    Trimethoprim is effective in stopping the growth and multiplication of bacteria that caused the infection.

    Trimethoprim is taken by mouth as a tablet or as a suspension. The dose of the medication, how often it needs to be taken, and how long it must be taken depends on the type and the severity of the infection. It is also determined by your kidney function.

    You should follow the instructions given by your doctor. The instructions on how to take trimethoprim are also printed in the dispensing label that comes with the medication.

    Trimethoprim can be taken with or without a meal.

    Trimethoprim should be taken at regular intervals. This will ensure that there is the same amount of medication in your bloodstream. If you forget to take a dose of trimethoprim, take it as soon as you remember. However, if it will be too close to your next dose, just skip the missed dose.

    Unless instructed by your doctor, you need to finish the prescribed course of treatment even if you start to feel better. Stopping the course of treatment before its completion increases the risk of the infection coming back, with the bacteria becoming resistant to the antibiotic.

    Trimethoprim is normally taken once in the morning and once in the evening, with a meal or without a meal.

    The usual dose of trimethoprim is as follows:

    • For the treatment of water infections – 200 mg two times a day. Your doctor may prescribe the first dose at 400 mg two times a day on the first day.
    • For the prevention of infections – 100 mg once a day.
    • For the treatment of cystitis that appears after having sex – 1 dose of 100 mg.
    • For the treatment of acne – 300 mg two times a day. The doctor may reduce the dose over time.

    The dose of this antibiotic depends on your infection, your age, and how well your kidneys work. Elderly people and individuals with kidney problems are typically prescribed lower doses of the medication.

    The use of trimethoprim may result in common and serious side effects. The common side effects of this antibiotic may include a mild rash or itching. The mild side effects will go away after you stop taking the medication.

    The use of trimethoprim may also result in diarrhoea or may make you feel sick. It may also result in headaches. Immediately notify your doctor if the side effects persist or get worse.

    The use of trimethoprim may result in rare cases of severe side effects. The chance of getting the severe side effects is very slim, one in a thousand people. Immediately notify your doctor if you experience:

    • Weakness of the muscles, inability to move or feel anything, chest pains, abnormal heartbeat, and feeling sick, which are symptoms of high levels of potassium in the blood.
    • Muscle cramps, headaches, and feeling sick or confused, which are signs of the presence of salt in your blood.
    • Serious rashes or skin reactions, irregular or round red patches, blisters, skin ulcers, peeling or swelling of the skin like burns.
    • Severe diarrhoea accompanied by diarrhoea with blood or mucus, which lasts longer than 4 days.
    • Fever, tiredness, stick neck, headaches, and sensitivity of eyes to bright light, which may be signs of meningitis.
    • Unexplained bruising or bleeding, high temperature, sore throat, and mouth ulcers, which could be signs of blood problems.

    In very rare cases, you may have a serious allergic reaction to trimethoprim, which may include:

    • Skin rash with itchy, swollen, and blistered skin
    • Tightness in the chest or throat
    • Wheezing
    • Difficulty in talking or breathing
    • Swelling of the face, lips, throat, tongue, and the mouth.

    Immediately call your doctor or the emergency medical service if you experience the symptoms of a serious allergic reaction.

    If you are taking trimethoprim, you should avoid exposure to sunlight or tanning beds. The use of the medication can make you sunburn easily. It is important to wear protective clothing and use sunscreen when you go outdoors.

    Trimethoprim is not to be taken by individuals who are allergic to it or to any of its ingredients. Consult your doctor before using trimethoprim if you have previously experienced an allergy to any medication. If you are taking trimethoprim and suddenly you experience an allergic reaction, stop taking the medication and immediately contact your doctor.

    The use of trimethoprim may decrease the levels of blood cells in your blood. You should immediately inform your doctor if you experience any symptoms of low blood cells such as a feeling of tiredness or general illness, high body temperature, sore throat, mouth ulcers, purple spots and bruising or bleeding. Your doctor may ask you to take a blood examination to check your blood cell count.

    The use of trimethoprim may rarely cause acute skin rashes, which could be fatal. You need to seek emergency medical treatment when you experience this. Immediately report to your doctor if you experience skin blistering, peeling, itching, rash, and other unexplained skin conditions while taking trimethoprim.


    Trimethoprim may cross the blood-placenta barrier in animal studies although it is not yet confirmed in the case of human pregnancy. The doctor must weight the benefits of the medicine against the potential risks when administering to pregnant women.

    Trimethoprim is not to be used by individuals with liver and kidney problems, blood system diseases, and anaemia.

    The risks of nursing infants have not been established. Doctors should evaluate the potential against the risks when administering this medication to breastfeeding mothers.

    You can safely buy Trimethoprim online at UK Meds. You will need to have first an online consultation with a medical doctor before your order will be supplied. The online consultation will ensure that Trimethoprim is the right medication for your medical condition.

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