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- Wegovy Pill (Oral Semaglutide Tablet)
Wegovy Pill (Oral Semaglutide Tablet)
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Start Your Weight Loss Consultation
✓ Currently pending MHRA approval in the UKWegovy Pill (oral semaglutide tablet) is a once-daily prescription weight loss treatment containing semaglutide, a GLP-1 receptor agonist clinically proven to suppress appetite and support weight reduction in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related comorbidities.
- Needle-free, once-daily oral tablet
- Mimics natural hunger hormones to increase satiety
- Clinically shown to reduce body weight by up to 16.6%
- Prescribed by UK-registered clinicians with discreet delivery
More information
Wegovy for Weight Loss: A Doctor’s Explanation

GP and surgeon Dr Shane Charles (MBBS, MRCS, PgDip SEM) explains how Wegovy works:
“Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist that has shown efficacy in promoting weight loss and in the management of type 2 diabetes mellitus (T2DM).”
If you think this treatment may be suitable for you, you can begin an online consultation. A registered prescriber will review your information.
Buying Wegovy Tablets Online at UK Meds
Whilst you can't currently purchase the Wegovy pill in the UK, if it becomes available, you can request to buy Wegovy tablets online through our secure digital platform. Because oral semaglutide is a prescription-only medication, safety is our priority. Our process is simple:
- Complete a Consultation: Fill out a short medical questionnaire regarding your weight, medical history and current medications.
- Clinical Review: An independent GPhC-registered prescriber reviews your assessment to ensure the Wegovy pill is safe and suitable for you.
- Discreet Delivery: If approved, your prescription is dispensed from our UK pharmacy and dispatched via tracked delivery in unmarked packaging.
Note: Availability is subject to MHRA approval and stock levels. If the treatment is not suitable, our clinicians may recommend appropriate alternatives.
Wegovy Oral Tablet Pricing
We strive to offer competitive pricing for oral Wegovy for weight loss when it becomes available. Costs may vary depending on whether you are in the titration phase (starting doses) or the maintenance phase.
- Starter Pack (Months 1-2): Lower dosage strengths (1.5 mg and 4 mg) are typically priced lower to help you start your journey.
- Maintenance Pack (Month 3+): The therapeutic doses (9 mg and 25 mg) are priced to reflect the higher concentration of the active ingredient needed for sustained weight loss.
Please refer to the product selection options for the most up-to-date oral Wegovy cost if/when the product becomes available.
Delivery Options
We understand that privacy and speed are essential when ordering weight loss pills.
| Method | Cost | Cut-off Time |
|---|---|---|
| Next-Day Delivery | From £4.95 | Order by 2:30pm (Mon-Thu) |
| DPD Next-Day (Pre-12pm) | £9.95 | Priority Morning Slot |
| Friday Orders | - | Dispatch on Monday (unless Saturday delivery is selected). |
All packaging is plain and tamper-evident, ensuring your privacy is protected.
What is the Wegovy pill?
The Wegovy pill is the first oral formulation of a GLP-1 receptor agonist approved for chronic weight management. It is designed for adults living with obesity or overweight who struggle to lose weight through diet and exercise alone.
Unlike traditional weight loss stimulants, oral semaglutide works hormonally. It targets the appetite centres in the brain to lower hunger levels and slows down gastric emptying (the speed at which food leaves your stomach), helping you feel fuller for longer.
Active Ingredients
The active ingredient in Wegovy tablets is semaglutide. Each tablet also utilises a unique absorption enhancer called SNAC (sodium N-[8-(2-hydroxybenzoyl) amino] caprylate), which temporarily lowers stomach acidity, allowing semaglutide to be absorbed into the bloodstream before it is broken down by digestion.
User Experiences with Oral Semaglutide
Clinical trials, such as the OASIS-4 study, have highlighted the efficacy of semaglutide oral for weight loss. Findings published in the British Medical Journal (BMJ) and other sources indicate that participants taking the 25mg daily dose lost an average of 16.6% of their body weight over 64 weeks, compared to just 2.4% in the placebo group.
Users often report a significant reduction in "food noise" (intrusive thoughts about food) within the first few weeks of treatment.
Patient Information Leaflet (PIL)
Every order of Wegovy tablets in the UK comes with a manufacturer-issued Patient Information Leaflet. This document contains vital information regarding safety, storage, and usage. We strongly advise you to read this leaflet fully before taking your first dose. A digital version is also available via the Electronic Medicines Compendium (EMC).
How does the treatment work?
Semaglutide oral functions by mimicking Glucagon-like peptide-1 (GLP-1), a natural hormone released by the gut after eating.
- Appetite Regulation: It signals the brain that you are satisfied, reducing hunger.
- Stomach Emptying: It slows the transit of food, prolonging the feeling of fullness.
- Blood Sugar Control: It improves the body's insulin response, which can help reduce sugar cravings.
How to Use Wegovy Tablets
Correct administration is critical for the Wegovy pill to work effectively. Because stomach acid can destroy the medication, strict adherence to the following routine is required:
- Take on an empty stomach: Consume immediately upon waking.
- Water only: Swallow the tablet whole with a sip of water (no more than 120ml).
- Wait 30 minutes: You must wait at least 30 minutes before eating, drinking, or taking other oral medications.
Failure to wait the full 30 minutes may significantly reduce the amount of semaglutide your body absorbs.
Dosage and Titration

To minimise side effects, oral semaglutide dosage for weight loss follows a step-up (titration) schedule. Your prescriber will guide you through these steps:
- Month 1: 1.5 mg daily (Starting dose)
- Month 2: 4 mg daily
- Month 3: 9 mg daily
- Maintenance: 25 mg daily
Do not increase your dose faster than prescribed.
Side Effects

Independent pharmacist Monalisa Kapinga explains the most common side effects:
"Wegovy can cause digestive effects like nausea, vomiting, diarrhoea and constipation, which usually improve as your body adjusts. Eating smaller, low-fat meals and staying hydrated can help. Tiredness and dizziness are also common early on. Seek urgent medical help if you experience severe abdominal pain (pancreatitis) or signs of an allergic reaction."
Like all medications, Wegovy pills can cause side effects, although not everyone gets them. Most are mild and transient, improving as your body adjusts.
- Very Common: Nausea, diarrhoea, constipation, vomiting.
- Common: Heartburn, bloating, gas, fatigue, headache, dizziness.
- Serious (Rare): Pancreatitis (severe abdominal pain), gallbladder issues (gallstones), allergic reactions.
If you experience severe symptoms, stop taking the medication and seek immediate medical attention.
Warnings and Precautions
Oral Wegovy is not suitable for everyone. Do not take this medication if:
- You have a personal or family history of Medullary Thyroid Carcinoma (MTC).
- You have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). [Image of thyroid gland anatomy]
- You are pregnant or breastfeeding (Semaglutide must be stopped 2 months before planned pregnancy).
- You have severe kidney or liver failure.
Comparison: Wegovy Pill vs Injection
Many patients ask: Wegovy pill or injection? Both contain semaglutide, but they differ in administration and bioavailability.
| Feature | Wegovy Pill (Oral) | Wegovy Injection (Pen) |
|---|---|---|
| Administration | Once daily tablet | Once weekly injection |
| Convenience | Needle-free, but requires strict morning fasting (30 mins). | Quick weekly dose, no food restrictions. |
| Efficacy (Trials) | ~16.6% weight loss (OASIS-4) | ~15-17% weight loss (STEP trials) |
| Dosage | Up to 25 mg (higher dose to offset digestion) | Up to 2.4 mg |
| Availability | Unavailable in UK (Early 2026) | Available in UK |
Frequently Asked Questions
Can you get Wegovy in pill form?
The Wegovy pill (oral semaglutide) was approved in the US in early 2026 and is currently under review by the MHRA for the UK market. It serves as a needle-free alternative to the injectable pen. It is not yet available to buy in the UK.
Is oral semaglutide effective for weight loss in non-diabetics?
Yes. While semaglutide was originally developed for diabetes, the Wegovy oral tablet is specifically licensed and dosed for weight management in people with or without diabetes, provided they meet the appropriate criteria.
What is the difference between oral semaglutide vs. traditional diabetes medicine?
Oral semaglutide is a GLP-1 receptor agonist that acts hormonally to suppress appetite. Traditional oral diabetes medications often work by stimulating insulin production or removing sugar via urine. Semaglutide is unique in its potent ability to induce weight loss alongside blood sugar control.
Does the Wegovy pill cost more than the injection?
Pricing structures can vary. In the US, introductory prices for the pill were lower than the injection, but maintenance doses are often comparable. Please check our pricing section for the current oral Wegovy cost in the UK, when it becomes available.
Can I switch from the injection to the pill?
Yes, switching from semaglutide injection to oral is possible. However, this must be done under the guidance of a clinician to ensure the correct dosage conversion is applied.
Medical Disclaimer
Our commitment to content accuracy
This content is regularly reviewed by our team of medical experts, including GPhC-registered pharmacists, to ensure it reflects the latest clinical guidelines (NICE) and research. Last reviewed: January 2026.
View Clinical References
- Dyer O. Pill version of obesity jab is approved in US, with UK decision pending. BMJ. 2026; 392:s2. Available at: https://www.bmj.com/content/392/bmj.s2
- Wharton S, et al. OASIS 4 Study Group. Oral semaglutide at a dose of 25 mg in adults with overweight or obesity. N Engl J Med. 2025.
- Novo Nordisk. Wegovy® (semaglutide) injection and tablets prescribing information. Electronic Medicines Compendium.
- National Institute for Health and Care Excellence (NICE). Obesity: identification, assessment and management. Available at: NICE Guidelines.
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