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Allopurinol is used to treat a number of ailments, including gout, kidney stones and enzyme disorders. It belongs to a group of medicines called enzyme inhibitors, which reduce the amount of uric acid your body produces.

Allopurinol tablets are an effective medication in preventing attacks of gout but should not be relied on or used during a gout attack, as it can actually prolong your episodes of gout. If you are already established on allopurinol and happen to experience a gout attack you should continue with it and take the necessary treatments such as NSAIDs and colchicine.

  • Prevents attacks of gout
  • Enzyme inhibitor medication
  • Lowers the amount of uric acid in the body
  • Genuine medication
  • All drugs sourced in the UK
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Buy Allopurinol

You can safely buy it here at UK Meds. You will first need to have an online consultation with a pharmacist independent prescriber before your order will be supplied. The online consultation will ensure that Allopurinol is the right medication for your medical condition.

Yes, you can get Allopurinol on a subscription from UK Meds. By getting your medication on a subscription you can rest assured that you will get it when you need it, whilst also saving money. It’s a win-win!

Allopurinol is a medicine used to lower levels of uric acid in your blood (NHS, 2023). Too much uric acid can build up and produce miniature sharp crystals to form around your joints, causing gout; this is extremely painful (NHS Inform, 2023).

It is also known by the brand names Zyloric and Uricto.

Type of drugXanthine oxidase enzyme inhibitor
Health conditions prescribed forGout
Active IngredientsAllopurinol
Brand namesZyloric, Uricto
Available strengths100mg, 300mg
Available asTablets
Possible side effectsNausea, vomiting
Patient Information LeafletFor more information on the medication please refer to the patient information leaflet for the Allopurinol.

For more information on the prescription medication patients should refer to the Allopurinol patient information leaflet.

Allopurinol works by actively lowering the levels of uric acid in your blood. Allopurinol comes as 100mg and 300mg tablets and is only available on prescription (NHS, 2023).

Swallow the allopurinol tablets with water, ideally after food. You'll usually take it once a day, but if you're on a high dose, your doctor may advise you to split the dose and take it twice a day. (NHS, 2023)

If your doctor has recommended you take allopurinol with lots of fluid, aim to consume at least 2 to 3 litres of fluids daily (Michael Stewart - BPharm, MRPharmS, 2021).

You can take Allopurinol at any time of the day, however, try to take your doses at the same time of day each day.

Your doctor or healthcare provider can advise you on the most appropriate way to take Allopurinol to suit your individual needs.

Video: How to take Allopurinol

In the below video Dr O'Donovan (UK GMC number: 7436647) explains how a patient would typically take Allopurinol tablets to treat gout:

Please be aware that the video above is only for educational purposes and is not intended for use as a substitute for seeking professional medical advice from your own doctor or trusted healthcare professional.

Allopurinol Reviews

See what gout patients have to say about their experiences with the medication by taking a look at the allopurinol user reviews and experiences available at and Web MD.

Allopurinol FAQs

The NHS (2023) advises caution if considering Allopurinol as a treatment if you are currently taking antibiotics, aspirin, medicines used for reducing immune response or diuretics tablets that make you pee more (e.g. furosemide) or ACE inhibitors (e.g. enalapril or ramipril).

Your doctor or healthcare provider will be able to advise you on what the best and safest course of treatment for your health condition is.

No, allopurinol is considered as a very safe long term treatment and it is unlikely to lead to any long-term side effects (NHS, 2023).

Whilst it is not always the case, allopurinol can have a risk of precipitating acute attacks of gout (NICE, 2023). This is because some of the urate crystals in the blood can dislodge into the joint as they become smaller, triggering the gout attack (Versus Arthritis, 2024). It is important to continue taking Allopurinol if you do experience an attack of gout (NHS West Essex Clinical Commissioning Group, 2018). You should always consult your doctor before starting treatment with Allopurinol to ensure that it is safe for your needs.

Yes, colchicine can be taken with allopurinol for prophylaxis of gout flares during urate-lowering treatment (NICE, 2023). Your doctor or healthcare provider can advise on which medications are the most suitable treatment for your health condition which is why it is important to consult them prior to starting any form of treatment.


Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled content writer dedicated to creating helpful and accessible medical content for UK Meds.

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Medical Reviewer

Medical Reviewer

Alexis Missick

General Practitioner (GP) • MBChB

With a decade of experience in the NHS and six years internationally, Alexis is a seasoned General Practitioner hailing from Turks and Caicos.

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