Cialis (Tadalafil)

You can buy Cialis (tadalafil) safely online in the UK through regulated services like UK Meds. Since the patent for tadalafil expired in 2017, both branded and generic versions have become more affordable and widely available. Tadalafil works the same way as Cialis to treat erectile dysfunction and is often well tolerated by users.

Is It Legal to Buy Cialis Online in the UK?

Yes, it’s legal to order Cialis or tadalafil online in the UK, as long as it’s done through a licensed provider and supported by a valid prescription. At UK Meds, you can complete a free online consultation, which is reviewed by a registered prescriber. If approved, your medication is dispensed by a UK-registered pharmacy and delivered discreetly to your door.

Do I Need a Prescription for Cialis?

Yes. Cialis and tadalafil are prescription-only medicines (POMs). You don’t need to have a prescription already, UK Meds provides a secure online consultation, and if the treatment is suitable for you, a registered prescriber will issue one at no extra cost.

Why Is Cialis Cheaper Online?

Buying Cialis online from UK Meds is often more affordable and cost-effective than in-store due to lower overheads. With no high street premises to maintain, we’re able to offer competitive prices while still providing safe and regulated prescription treatments.

Can I Get Cialis on Subscription?

Yes. UK Meds offers a subscription service for Cialis (tadalafil), so your treatment is delivered regularly without the need to reorder. Subscriptions can also offer better value compared to one-off purchases.

Is Cialis Available in My Area?

Find yourself searching for "Cialis near me" or "Tadalafil near me"? If so, you can order Cialis online from anywhere in the UK, including major cities like London, Manchester, Birmingham, and Leeds. After completing the online consultation, your medication will be delivered to your home with discreet packaging and fast shipping.

• Cialis in London
• Cialis in Manchester

Important: All requests for Cialis or tadalafil are reviewed by a registered independent prescriber. Medication is only supplied if the treatment is considered safe and appropriate for you.

Choose the Best Delivery Options

Decide on the best discreet delivery option for your order below.

Please note: Delivery options and pricing are subject to change. For the latest information on UK Meds delivery options please visit our delivery page to learn more. You can also read our other policies including our returns process.

Choose the best cost option for you:

Starting prices for all pack sizes.
Strengths available: 2.5mg, 5mg, 10mg and 20mg

Please note: Pricing is subject to change. For the latest information please refer to the consultation section at the top of the product information page. 

Always read the patient information leaflet inside your medicine box before you start treatment. We've provided the PIL for each strength of Cialis and tadalafil below:

Cialis® information leaflet

• Cialis 2.5mg patient information leaflet
• Cialis 5mg patient information leaflet
• Cialis 10mg patient information leaflet
• Cialis 20mg patient information leaflet

Tadalafil information leaflet

• Tadalafil 2.5mg patient information leaflet
• Tadalafil 5mg patient information leaflet
• Tadalafil 10mg patient information leaflet
• Tadalafil 20mg patient information leaflet

Cialis (tadalafil) is well-reviewed by many men who use it for erectile dysfunction (ED). Users often report feeling more confident and enjoying a better sex life.

• Real experiences: Check reviews from UK Meds customers above to see how Cialis has helped others in the UK.
• More reviews: You can also read user feedback on trusted sites like Drugs.com and WebMD.

Is Cialis right for me?

Cialis works differently for everyone. Some people notice results quickly, while others may need to try it a few times before it helps.

1. Speak to your doctor: Always get medical advice first to make sure Cialis is safe and suitable for you.
2. Listen to your body: Reviews are useful, but your personal experience is the most important.

Follow your healthcare provider’s instructions when starting any new medication.

Watch Dr Andrew Hart-Pinto explain everything you need to know about Cialis in this overview by JHP Medical UK.

What Is Cialis (Tadalafil)?

Cialis is a prescription medicine used to treat erectile dysfunction (ED). Its active ingredient, tadalafil, helps increase blood flow to the penis, making it easier to get and maintain an erection during sexual activity. Often called the “weekend pill,” its effects can last up to 36 hours.

Tadalafil is also the name of the generic version of Cialis. It contains the same active ingredient, works in the same way, and typically costs less. Both options are available at UK Meds.

Available Tadalafil Treatments at UK Meds:

• Generic Tadalafil: Lower-cost alternative to branded Cialis
• Cialis Daily: A low-dose version taken daily for ongoing support
• Cialis Together: An over-the-counter version available without a prescription

If you don’t have a prescription, simply complete a free online consultation reviewed by a registered UK prescriber.

How Does Cialis Work?

Tadalafil works by relaxing blood vessels and increasing blood flow to the penis. It blocks an enzyme called phosphodiesterase type 5 (PDE5), which normally constricts blood flow. By inhibiting PDE5, Cialis helps maintain erections and also improves symptoms of benign prostatic hyperplasia (BPH) in some men (Fahmy & Hess, 2024; Coward & Carson, 2008).

Note: Cialis does not increase sexual desire. If low libido is a concern, speak to your doctor about other treatment options.

Is Generic Cialis the Same as Branded?

Yes. Generic tadalafil and branded Cialis contain the same active ingredient and are clinically equivalent in effectiveness and safety. The main difference is price, generic versions are typically more budget-friendly.

How Effective Is Cialis?

Cialis has been shown to be highly effective for treating erectile dysfunction. In clinical trials, over 80% of men achieved improved erections compared to those using a placebo (Skoumal et al., 2004).

• Effects can last up to 36 hours, offering greater flexibility than other ED medications
• It may take up to 8 uses to evaluate its effectiveness fully
• Often works well for older adults and men with diabetes
• May be less effective after pelvic surgery or prostate removal

As with all medications, results can vary. Speak to a healthcare provider to find the best treatment for your needs.

How Do You Take Cialis?

Take one Cialis (tadalafil) tablet about 30 minutes before sex, unless you're on a daily low-dose version. Cialis can be taken with or without food, swallow the tablet whole with water. The medication only works when you're sexually aroused.

• Do not take it with other erectile dysfunction treatments
• Follow your prescribed dose, do not exceed one tablet in 24 hours
• Speak to your GP or pharmacist if you're unsure how to take it

Tips for First-Time Users

• Use Cialis only if it’s been prescribed for you
• Don’t share your medication with others
• Try it up to 8 times before judging effectiveness
• Discuss any side effects or concerns with a healthcare professional

Taking Cialis correctly helps maximise results and minimises the risk of side effects.

How Long Does Cialis Take to Work?

Cialis typically starts working within 30 minutes but requires sexual arousal to be effective. Its effects can last up to 36 hours, making it a flexible option for spontaneous activity.

How Long Should I Take Cialis For?

You can continue taking Cialis for as long as your doctor recommends. There are no known risks with long-term use when taken as prescribed.

• Use it only when needed or daily, depending on your treatment plan
• Attend regular check-ups to ensure it remains suitable for you

Cialis (tadalafil) is available in four strengths: 2.5mg, 5mg, 10mg, and 20mg. The best dose for you depends on how often you plan to have sex, your overall health, and your prescriber’s recommendation.

Cialis Dosage Guide

• 2.5mg: A lower daily dose option, often used if 5mg causes side effects
• 5mg: Standard daily dose, ideal for regular sexual activity (more than twice a week)
• 10mg: Recommended starting dose for as-needed use, taken 30 minutes before sex
• 20mg: Higher strength for those who don’t respond to 10mg, but only increase on medical advice

How to Take Cialis

Things to Remember

• Follow the dose prescribed by your doctor or prescriber
• Daily Cialis is better for frequent use; as-needed doses are suitable for occasional use
• Your dose may be adjusted based on effectiveness or side effects

If you’re unsure which dosage is right for you, speak to a GP, pharmacist, or registered prescriber before starting treatment.

What Are the Side Effects of Cialis?

Most people tolerate Cialis (tadalafil) well, but like all medications, it can cause side effects. These are usually mild and temporary but can occasionally be serious.

Common Side Effects (Up to 1 in 10 users)

• Headache
• Indigestion or upset stomach
• Stuffy or blocked nose
• Back pain
• Muscle aches

These symptoms usually improve within a few hours. If they persist or cause discomfort, speak to your doctor or pharmacist.

Rare but Serious Side Effects

Although uncommon, some side effects may require immediate medical attention:

• Chest pain
• Irregular or fast heartbeat
• Sudden hearing loss or ringing in the ears
• Severe allergic reaction (rash, swelling, difficulty breathing)
• Very low or high blood pressure
• Priapism: An erection lasting longer than 4 hours without sexual stimulation (Silberman et al, 2023)

Important: Priapism is a medical emergency and requires immediate treatment to avoid long-term damage.

How Long Do Side Effects Last?

Common side effects like headaches or flushing usually pass within a few hours. Back pain and muscle aches may last up to 48 hours. Always contact a healthcare professional if symptoms persist or worsen.

How to Reduce the Risk of Side Effects

• Start with the lowest dose recommended by your prescriber
• Read the patient information leaflet before use
• Avoid taking Cialis with other ED treatments or nitrates
• Report any unusual or long-lasting symptoms to your doctor

Tips for Managing Mild Side Effects

• Stay hydrated: Helps your body process the medication
• Avoid greasy or spicy foods: Can reduce the risk of indigestion
• Stay cool: If you feel flushed, a cool environment can help
• Speak to a pharmacist: They may suggest remedies for stomach upset or headache

Can You Eat Grapefruit While Taking Cialis?

No. Grapefruit and grapefruit juice can interfere with how your body processes tadalafil, potentially increasing the risk of side effects.

Tip: Avoid grapefruit products during treatment and for a few days after your last dose. If in doubt, ask your doctor or pharmacist.

Always read the leaflet provided with your medication and consult a healthcare professional to ensure Cialis is safe and appropriate for you.

What Should I Know Before Taking Cialis?

Cialis (tadalafil) is generally safe when taken as prescribed, but there are some important precautions to be aware of.

When Not to Take Cialis

You should not take Cialis if you:

• Use nitrate medications (e.g. GTN spray or isosorbide mononitrate) for chest pain
• Take recreational drugs like amyl nitrate, commonly known as poppers

Combining Cialis with nitrates or poppers can cause a dangerous drop in blood pressure and may lead to serious health complications.

Is Cialis Addictive?

Cialis is not physically addictive, meaning you won’t experience withdrawal symptoms if you stop taking it. However, some people may become psychologically reliant on the medication for confidence or sexual performance.

• Use only as prescribed and avoid overuse
• If you’re concerned about dependency, speak to your doctor or pharmacist

Always follow medical advice and read the patient leaflet before starting Cialis. If you’re unsure whether it’s suitable for you, consult a healthcare professional.

Find answers to common questions about Cialis (tadalafil) from UK Meds customers to help you use the treatment safely and effectively.

Can I Drink Alcohol While Taking Cialis?

It’s best to limit or avoid alcohol when taking Cialis. Both alcohol and tadalafil can lower your blood pressure, and using them together may cause dizziness, headaches, or heart-related issues. Drinking less alcohol can also help maximise the effectiveness of the medication. Always follow your prescriber’s advice regarding alcohol use.

Can I Become Dependent on Cialis?

Cialis is not physically addictive and won’t cause withdrawal symptoms. However, some people may become psychologically reliant on it, especially if they use it for confidence or performance anxiety. If you feel you’re depending on it, speak to a healthcare professional for support.

Are There Medicines I Shouldn’t Take With Cialis?

Yes. Cialis can interact with some medicines, especially those used to treat chest pain or high blood pressure. Always inform your doctor or pharmacist about all medications, supplements, or recreational substances you use before starting Cialis.

Avoid Cialis if You’re Taking:

• Nitrates (e.g. GTN spray, isosorbide mononitrate)
• Poppers (amyl nitrate)
• Riociguat (used for pulmonary hypertension)
• Certain herbal supplements

Combining these with Cialis can cause a dangerous drop in blood pressure. Always check with your healthcare provider first.

Is Cialis Stronger Than Viagra?

Not exactly. Cialis and Viagra both treat erectile dysfunction but differ in how long they last:

• Cialis: Works for up to 36 hours
• Viagra: Lasts around 4 to 6 hours

While Cialis has a longer duration, one isn’t stronger than the other. Your doctor can help you choose based on how often you need the medication and your lifestyle.

What Else Is Cialis Used For?

Besides erectile dysfunction, Cialis (tadalafil) is sometimes prescribed for:

• Benign Prostatic Hyperplasia (BPH): To relieve urinary symptoms caused by an enlarged prostate
• Pulmonary Hypertension: To help reduce blood pressure in the lungs and ease strain on the heart

These uses should only be considered after a full assessment by a healthcare professional.

Does Cialis Treat Premature Ejaculation?

Cialis is not licensed for premature ejaculation (PE). However, in men with both PE and erectile dysfunction, it may help with ejaculation control (Karabakan et al, 2017; Abou Faddan et al, 2022).

Results vary and Cialis is not a first-line treatment for PE. Speak to your doctor about options tailored to your needs.

What Are the Alternatives to Cialis or Viagra?

If Cialis or Viagra isn’t suitable or effective, there are several other treatments for erectile dysfunction (ED), including lifestyle changes, therapy, and alternative medications. A healthcare professional can help you choose the best option based on your individual needs.

1. Counselling and Therapy

When ED is linked to anxiety, stress, or low libido, therapy can be beneficial. Speaking to a trained counsellor may help improve sexual confidence and mental wellbeing.

• Cognitive behavioural therapy (CBT) and talking therapies are often recommended.
• NHS counselling services may be available—ask your GP for advice.

2. Lifestyle Changes

Improving your general health can support better blood flow and natural erections. Consider:

• Eating a balanced, nutritious diet
• Exercising regularly
• Quitting smoking and limiting alcohol

These changes can also help manage underlying conditions like high blood pressure and heart disease (Yannas et al., 2021).

3. Alternative ED Medications

There are other treatment options if standard ED tablets aren’t suitable or haven’t worked:

Topical ED Creams

• Vitaros (Alprostadil): A fast-acting cream applied directly to the penis

Alternative Tablets

• Sildenafil (Viagra) or Viagra Connect
• Spedra (Avanafil)
• Levitra (Vardenafil)

How Do I Choose the Right Treatment?

Choosing the best ED treatment depends on your medical history, lifestyle, and how often you need support. A GP or registered prescriber can guide you through your options and recommend what’s safest and most effective for your situation.

UK Meds is committed to providing you with the most accurate information possible regarding healthcare and lifestyle, as outlined in our Editorial Policy and Content Policy. We aim to regularly peer review and update our content as necessary to give you the most up-to-date medical information, helping you to be fully informed before starting a consultation with a registered prescriber for the treatment that you need.

Please note that our content is not a substitute for professional medical advice. Before starting any treatment or making any changes that could affect your lifestyle, you should always speak with your doctor, pharmacist or healthcare provider to ensure that it is safe and suitable for you.

10th July 2025

• NHS - Tadalafil
• Patient.info - Tadalafil for erectile dysfunction or enlarged prostate
• European Medicines Agency - Cialis
• Drugs.com - Cialis
• British National Formulary (BNF) - Tadalafil

• How to Get the Best Results from Cialis - Tips to maximise the effectiveness of Cialis for ED treatment.
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• Can I Get Cialis Without A DocotrPrescription? - A guide explaining over the counter options for tadalafil
• Cialis vs Viagra: Which Is Best? - Compare Cialis and Viagra to find the best option for your needs.
• Viagra vs Levitra vs Cialis - A detailed comparison of these three popular ED medications.
• Taking Erectile Dysfunction Medication with Alcohol - Learn if it’s safe to mix ED drugs like Cialis with alcohol.
• Can I Take ED Drugs After a Heart Attack? - Understand if it’s safe to use ED medications after a heart condition.
• Alternatives to Viagra - Explore other options beyond Viagra for treating ED.
• Erectile Dysfunction Medication - Explore available medications for managing erectile dysfunction.
• What Causes Erectile Dysfunction? - Learn about the common reasons behind erectile dysfunction.