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Cialis (Tadalafil)

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Cialis (tadalafil) is the famous "Weekend Pill" for erectile dysfunction (ED). Because it remains effective for up to 36 hours, you can buy Cialis online to enjoy spontaneous intimacy without strict timing.

From £11.50 per pack.

Generic vs Branded: Generic Cialis (Tadalafil) contains the same active ingredient as the brand. It works exactly the same way but is the cheapest Cialis option available.

Also available: Cialis Daily (for everyday use) and Cialis Together (No prescription needed).

  • Long Lasting: Active for up to 36 hours.
  • Best Value: We offer the cheapest Tadalafil UK stock from just 59p per tablet.
  • Flexible: Effective with or without food.
  • Discreet: Delivered in plain, unbranded packaging.
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Cialis for Erectile Dysfunction: A Doctor’s Explanation

Dr Shane Charles (MBBS, MRCS, PgDip SEM) - GMC Number 8085739

GP and surgeon Dr Shane Charles (MBBS, MRCS, PgDip SEM) explains:

"Cialis (tadalafil) is a long-acting PDE5 inhibitor used to manage male erectile dysfunction. It is often preferred because it stays active in the body for up to 36 hours, allowing for greater spontaneity compared to other treatments."

If you think this treatment is right for you, you can begin an online consultation. A registered prescriber will review your suitability. If approved, your medication is delivered discreetly to your door.

Where to Buy Cialis Online in the UK?

If you are looking to buy Cialis online in the UK, UK Meds provides a safe service. Our platform connects you with independent prescribers and GPhC-registered partner pharmacies.

  • Cheap Tadalafil UK: Generic prices start from just 59p per tablet.
  • Total Privacy: Delivered in plain, unbranded packaging.
  • Fast Delivery: Next-day shipping available (including Saturdays).
  • Subscriptions: Save time with automatic repeat deliveries. See how we compare to Numan and Hims.

Can I Order Cialis Online Without a Prescription?

Standard Cialis 10mg or 20mg is a prescription-only medicine, meaning you cannot buy it "off the shelf." However, you do not need to visit a GP first. When you order Cialis online at UK Meds, we provide a free private prescription included in the cost after you complete our medical consultation.

If you specifically want to buy Cialis without a doctor prescription, you should choose Cialis Together, which is available over-the-counter for men aged 18+.

Cheapest Cialis & Tadalafil Prices UK

You can choose between Cialis (Lilly) and Generic Tadalafil. Both contain the exact same active ingredient and work in the same way, but Tadalafil is the cheapest Cialis UK option.

Tadalafil vs Cialis Price Comparison (Starting Prices)
QuantityPack PriceCost Per Tablet
1 Month (28 tablets)£18.89£0.67
2 Months (56 tablets)£35.99£0.64
3 Months (84 tablets)£49.4959p

*Prices shown for Generic Tadalafil. Branded Cialis prices are higher due to manufacturing costs.

What is the difference?

  • Cialis: The original brand manufactured by Eli Lilly. It is well-known but more expensive.
  • Tadalafil (Generic Cialis): The unbranded version. It is clinically identical, equally effective, and the cheapest Cialis online option.

Which Cialis Version Do I Need?

There are three main ways to take Tadalafil. Use this table to decide which suits you best:

ProductStrengthsHow to TakeBest For
Cialis / Tadalafil10mg, 20mg30 mins before sexWeekend use (36 hours)
Cialis Daily2.5mg, 5mgOnce every daySpontaneous sex anytime
Cialis Together10mg30 mins before sexBuying without a prescription

How Effective is Cialis? (Clinical Data)

Cialis (tadalafil) is highly effective. In clinical studies, over 80% of men achieved improved erections compared to placebo[1].

  • Duration: It remains effective for up to 36 hours, earning it the nickname "The Weekend Pill"[2].
  • Success Rate: It works well for most men, including those with diabetes or high blood pressure[3].
  • Reliability: It may take up to 8 attempts to fully gauge effectiveness.

How Does Cialis Work?

Tadalafil belongs to a group of medicines called PDE5 inhibitors. It relaxes blood vessels, allowing blood to flow into the penis when you are sexually aroused.

  • Requires Stimulation: Cialis will not cause an erection on its own; you must be aroused.
  • Onset: Typically works within 30 minutes.
  • Freedom from Timing: Because it lasts 36 hours, you don't need to "time" sex precisely.

How to Take Cialis for Best Results

  1. Timing: Swallow one tablet with water at least 30 minutes before sex.
  2. Food: Unlike Viagra, Cialis can be taken with or without food without affecting its speed.
  3. Alcohol: Limit alcohol intake. Excessive drinking can reduce the drug's effectiveness and increase dizziness.
  4. Frequency: Do not take more than one tablet in 24 hours.

Video: How and When to Take Cialis

Watch Dr Andrew Hart-Pinto explain how Cialis works and how to get the best results in this video by JHP Medical UK.

Who Can Take Cialis? (Safety Information)

Cialis is suitable for men aged 18+ with erectile dysfunction. However, it can interact with certain conditions and medicines.

⚠️ Important Safety Warnings

Do NOT take Cialis if you:

  • Take nitrate medicines (e.g., GTN spray) for chest pain. This combination can cause a dangerous drop in blood pressure.
  • Take "poppers" (recreational amyl nitrate).
  • Take Riociguat for pulmonary hypertension.
  • Have severe heart or liver problems or have recently had a stroke or heart attack.
  • Have low blood pressure.

Grapefruit Warning: Avoid grapefruit juice while taking Tadalafil, as it can affect how the medicine is processed and increase side effects.

Can I Become Dependent on Cialis?

Cialis is not physically addictive, meaning you won’t experience withdrawal symptoms if you stop taking it. However, some men may develop a psychological reliance, feeling they cannot perform without it due to confidence or anxiety issues. If you are concerned about dependency, speak to your prescriber.

Ingredients

The active ingredient is tadalafil.

View inactive ingredients (Allergy Info)

Core: Lactose monohydrate, croscarmellose sodium, hydroxypropylcellulose, microcrystalline cellulose, sodium laurilsulfate, magnesium stearate.
Coating: Hypromellose, triacetin, titanium dioxide (E171), iron oxide yellow (E172), talc.

Side Effects

Dr Samantha Miller - GMC Number 7561464

Dr Samantha Miller explains common side effects:

"Common side effects of tadalafil include headache, flushing, blocked nose, indigestion, back pain, and muscle aches. These are usually mild and temporary. Stay hydrated and avoid alcohol. If you experience chest pain, vision loss, or a prolonged erection (priapism) lasting more than 4 hours, seek emergency medical help immediately."

For a full list of side effects, please read the official Cialis Patient Information Leaflet (PIL).

Alternative Erectile Dysfunction Treatments

If Cialis doesn't work for you, other ED treatments may be better suited to your lifestyle.

Comparison of ED Treatments
MedicationSpeed of ActionDurationBest For
Cialis / Tadalafil30 minsUp to 36 hoursSpontaneity & Weekends
Viagra (Sildenafil)30-60 mins4-5 hoursPlanned sex
Spedra15-30 mins4-5 hoursFastest action
Levitra25-60 mins4-5 hoursDiabetic men

Other ED Treatment Options:

  • Cialis Together: Pharmacy medicines available without a prescription.
  • Vitaros Cream: An alternative for men who cannot take tablets.
  • Penis Pumps: Vacuum devices that help achieve an erection without medication.

Non-Medicinal Treatments for ED

Medication is not the only way to treat erectile dysfunction. For many men, combining Cialis with lifestyle changes yields the best results.

  • Counselling & Therapy: If your ED is caused by stress, anxiety, or relationship issues, Cognitive Behavioural Therapy (CBT) or psychosexual counselling can be highly effective.
  • Lifestyle Changes: Quitting smoking, reducing alcohol intake, and regular cardiovascular exercise improve blood flow naturally, often enhancing the effect of medication.

Frequently Asked Questions

Do I need a prescription to buy Cialis?

Yes, standard Cialis and Tadalafil are prescription-only medicines (POM). You can get a private prescription online through UK Meds after a short consultation. Cialis Together is a pharmacy alternative available without a prescription but still requires a pharmacist check.

Is Cialis stronger than Viagra?

Not necessarily "stronger," but longer-lasting. Viagra lasts 4-5 hours, while Cialis lasts 36 hours. Both are highly effective, but Cialis offers more flexibility.

Does Cialis work for everyone?

It works for about 80% of men. If it doesn't work the first time, try up to 8 times before switching. Other options like Spedra or Vitaros may work if Cialis does not.

Does Cialis help with Premature Ejaculation?

Cialis is not licensed for premature ejaculation (PE). However, some studies suggest that in men with both PE and erectile dysfunction, it may help improve control (Karabakan et al, 2017). It is not a first-line treatment for PE; specific treatments like Priligy are usually recommended.

Delivery & Shipping

We understand the need for privacy. All orders are shipped in plain, discreet packaging with no branding visible on the outside.

MethodCostTimeframe
Standard Delivery£2.95 (Free over £50)3-4 working days
Next-Day Delivery£4.95Order by 2:30pm (Mon-Fri)
DPD Saturday£9.95Guaranteed Saturday delivery

Policies: Delivery options are subject to change. For full details, please read our Delivery Information, Site Policies, and Returns Process.

Start Your Journey

Get effective ED treatment delivered to your door in 3 simple steps:

  1. Complete the online consultation.
  2. Our registered prescriber reviews your answers.
  3. If approved, your medication is dispatched for discreet delivery.

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UK Meds Cialis Resource Hub

Clinical Studies & Medical References

  1. Efficacy (Skoumal et al., 2004): Skoumal et al. (2004) - "Efficacy and treatment satisfaction with on-demand tadalafil." European Urology.
  2. Duration (36 Hours): Washington & Shindel (2010) - "A once-daily dose of tadalafil for erectile dysfunction." Drug Design, Development and Therapy.
  3. Diabetes Efficacy: Gallo et al. (2020) - "The role of Tadalafil in the treatment of erectile dysfunction." Sexual Medicine Reviews.
  4. Premature Ejaculation: Karabakan et al. (2017) - "Effect of tadalafil 5 mg daily treatment on the ejaculatory time..." Urology Annals.

General Sources & Patient Leaflets

Our Commitment to Content Accuracy

UK Meds is committed to providing clear, accurate and up-to-date medical information in line with our Editorial Policy and Content Policy. All content is regularly reviewed to help you make informed decisions before starting a consultation with a registered prescriber.

Medical Disclaimer: The information on this page is not a substitute for medical advice. Always speak to a doctor, pharmacist or healthcare professional before beginning any treatment.

Page Last Updated: 11th December 2025

Author

Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled medical content writer dedicated to creating helpful and accessible health and wellbeing content for UK Meds.

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Medically Reviewed By:

Medically Reviewed By:

Alexis Missick

General Practitioner (GP) • MBChB

With over a decade of experience in the NHS and six years internationally, Alexis is a seasoned General Practitioner hailing from Turks and Caicos.

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