Cialis (Tadalafil)

Where can I buy Cialis online in the UK?

Buy Tadalafil

You can buy Cialis or its generic version, Tadalafil, online in the UK through trusted services like UK Meds. If you already have a prescription, we’ll process your order straight away. If not, simply complete a quick and free online consultation. A registered independent prescriber will review your answers and, if approved, you can place your order online.

Can I get Cialis on subscription?

Yes, UK Meds offers a Cialis (Tadalafil) subscription service. This ensures your medication is delivered regularly, so you never run out. Subscriptions can also be more cost-effective than one-off orders.

Is it legal to buy Cialis online in the UK?

Yes, buying Cialis or Tadalafil online is legal in the UK, provided you have a valid prescription. At UK Meds, all medication is dispensed by UK-registered pharmacies and is 100% genuine. You’ll need to complete a free online consultation to confirm the treatment is suitable for you.

Can I get Cialis without a prescription?

Cialis Together – Over-the-Counter Option

Yes, you can get Cialis over-the-counter without a prescription under the brand name "Cialis Together". However, you will need to have a consultation with a prescriber first, who will ask you a few questions to ensure it's suitable for you.

It's intended for adult men with erectile dysfunction and works by helping to improve blood flow, making it easier to get and keep an erection during sex.

Can I buy Cialis in London?

Cialis London

Yes, you can order Cialis online in London from UK Meds. If you have a prescription, you can complete your purchase easily. If not, you can fill in a short consultation, which will be reviewed by a registered independent prescriber. Once approved, your treatment will be delivered discreetly to your door. Always consult a healthcare professional before starting new medication.

For more details, read our Cialis London guide.

Can I buy Cialis in Manchester?

Cialis Manchester

Yes, you can buy Cialis online in Manchester via UK Meds. Place an order using your existing prescription or complete our free online consultation. After review by a registered independent prescriber, your medication can be delivered directly to your address. Always seek advice from a healthcare provider before starting Cialis.

Read our Cialis Manchester guide for more information.

Always read the patient information leaflet inside your medicine box before you start treatment. We've provided the PIL for each strength of Cialis and tadalafil below:

Cialis® information leaflet

• Cialis 2.5mg patient information leaflet
• Cialis 5mg patient information leaflet
• Cialis 10mg patient information leaflet
• Cialis 20mg patient information leaflet

Tadalafil information leaflet

• Tadalafil 2.5mg patient information leaflet
• Tadalafil 5mg patient information leaflet
• Tadalafil 10mg patient information leaflet
• Tadalafil 20mg patient information leaflet

What do users say about Cialis?

Cialis (tadalafil) is well-reviewed by many men who use it for erectile dysfunction (ED). Users often report feeling more confident and enjoying a better sex life.

• Real experiences: Check reviews from UK Meds customers above to see how Cialis has helped others in the UK.
• More reviews: You can also read user feedback on trusted sites like Drugs.com and WebMD.

Is Cialis right for you?

Cialis works differently for everyone. Some people notice results quickly, while others may need to try it a few times before it helps.

1. Speak to your doctor: Always get medical advice first to make sure Cialis is safe and suitable for you.
2. Listen to your body: Reviews are useful, but your personal experience is the most important.

Follow your healthcare provider’s instructions when starting any new medication.

What is Cialis (Tadalafil)?

Understanding Cialis and Tadalafil

Cialis is a popular treatment for erectile dysfunction (ED). It contains the active ingredient tadalafil.

• Tadalafil helps men get and keep an erection during sexual activity.
• It’s often called the "weekend pill" because it can work for up to 36 hours.
• Tadalafil is the generic version of Cialis and is usually cheaper.

Before using Cialis or tadalafil, speak to your doctor or pharmacist to check if it’s right for you.

Is there a generic version of Cialis?

Yes. Tadalafil is the generic drug form of Cialis. Generic drugs are an exact copy of an active drug in a branded medication. Generic drugs are generally considered to be as safe and effective as the original drug and tend to be cheaper than brand-name version of the drugs. It's been available in the UK since 2017 when the Cialis patent expired.

• Both contain the same active ingredient.
• They work the same and have the same possible side effects.
• The main difference is cost – tadalafil is more budget-friendly.

Tadalafil offers the same results at a lower price. A healthcare professional can help you decide which is best for you.

Cialis Options in the UK

You can buy the following at UK Meds:

• Generic tadalafil
• Cialis Daily and Cialis Together

If you don’t have a prescription, complete a free online consultation with a registered independent prescriber.

How Does Cialis (Tadalafil) Work?

Tadalafil, the active ingredient in Cialis tablets, works by relaxing blood vessels and improving blood flow to the penis. It is mainly used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). Tadalafil blocks an enzyme called phosphodiesterase type 5 (PDE5), which normally tightens blood vessels and muscles (Fahmy & Hess, 2024; Coward & Carson, 2008). By inhibiting PDE5, tadalafil helps keep blood vessels relaxed, supporting better erections and easing urinary symptoms in BPH.

• Note: Cialis does not increase sexual desire. If you have low libido, speak to your doctor about suitable treatment options.

How Effective Is Cialis?

Cialis (tadalafil) is widely used and clinically proven to help treat erectile dysfunction (ED). In studies comparing Cialis to a placebo, men experienced significant improvements in their ability to achieve and maintain an erection. While it's considered safe and effective for many, results can vary between individuals.

Cialis is known to be effective for a wide range of users:

• Over 80% of men report achieving a firm erection after using Cialis (Skoumal et al., 2004).
• The effects can last up to 36 hours, offering greater flexibility compared to other ED treatments.
• You may need to try it up to 8 times before deciding if it works for you.
• Often effective for older adults and people with diabetes, without needing a different dose.
• It may be less effective for men who have had pelvic surgery or a prostatectomy (prostate removal).

Cialis is a trusted option for managing erectile dysfunction. Always speak to a doctor or a registered prescriber to find out if it’s right for you and to discuss other suitable treatments if needed.

How do you take Cialis?

Cialis (tadalafil) comes in four strengths: 2.5mg, 5mg, 10mg, and 20mg. The right dose depends on how often you want to take it.

• Occasional use: Take 10mg or 20mg before planned sexual activity.
• Daily use: Take 2.5mg or 5mg once a day for more flexibility and spontaneity.
• Some men find that 5mg works well even when used occasionally.

Tips for First-Time Users

Cialis might not work straight away. Experts suggest trying it at least eight times before considering another option.

How to Take Cialis:

1. Take one tablet about 30 minutes before sex, unless you're on a daily dose.
2. Sexual arousal is required – Cialis only works if you’re turned on.
3. You can take it with or without food. Swallow the tablet whole with water.
4. Do not use with other ED medications – avoid taking Cialis within 24 hours of any similar treatment.

Follow the instructions from your doctor. If you’re unsure about your dose or how to take it, speak to a GP or pharmacist.

How long does Cialis take to work?

Cialis usually starts to work within 30 minutes, but only when you are sexually aroused.

• The effects can last up to 36 hours, earning it the nickname "the weekend pill".

How long should I take Cialis for?

You can use Cialis for as long as your doctor advises. There are no known risks with long-term use.

• Take it only when needed, or daily if prescribed.
• Make sure to have regular check-ups to see if it’s still the best option for you.

What Is the Recommended Dosage for Cialis (Tadalafil)?

Cialis (tadalafil) is available in four strengths: 2.5mg, 5mg, 10mg, and 20mg. The right dose depends on how often you need it, your health, and your prescriber’s recommendation.

Cialis Dosage Options

Cialis Daily (for regular use)

• 2.5mg: Lower dose option if 5mg causes side effects.
• 5mg: Standard daily dose, ideal if you have sex more than twice a week.

Cialis As Needed (for occasional use)

• 10mg: Common starting dose taken before planned sexual activity.
• 20mg: Used if 10mg isn't effective and no side effects occur. Only increase on medical advice.

Cialis Dosage Guidelines

36-Hour Cialis (occasional use)

Cialis Daily (everyday use)

Cialis Together (non-prescription version)

Key Points to Remember

• Always follow the dosage instructions given by your doctor or a registered prescriber.
• Daily Cialis is suitable if you’re sexually active more than twice a week.
• As-needed Cialis is better for occasional use.
• Your dose may be adjusted depending on how well it works or if you have side effects.

If you’re unsure which dose is right for you, speak to your GP, pharmacist, or a registered prescriber before starting treatment.

What Are the Side Effects of Cialis (Tadalafil)?

Cialis is usually well tolerated, but like all medicines, it can cause side effects. Most are mild and go away on their own.

Common Side Effects

These are reported by up to 1 in 10 people and typically improve without treatment:

• Headache
• Indigestion or upset stomach
• Blocked or stuffy nose
• Muscle aches
• Back pain

If these symptoms last or cause discomfort, speak to your doctor or pharmacist.

Rare but Serious Side Effects

These are uncommon but may need urgent medical attention:

• Chest pain
• Irregular or rapid heartbeat
• Sudden hearing loss or ringing in the ears
• Very low or high blood pressure
• Painful or prolonged erections lasting more than 4 hours (priapism)
• Severe allergic reactions – rash, swelling, or difficulty breathing

What Is Priapism?

Priapism is a rare condition where an erection lasts longer than 4 hours without sexual stimulation (Silberman et al, 2023). It requires emergency treatment to avoid permanent damage.

How to Reduce the Risk of Side Effects

• Start with the lowest dose recommended by your prescriber
• Read the patient information leaflet before use
• Tell your doctor if you experience any long-lasting or severe symptoms

How Long Do Cialis Side Effects Last?

Mild symptoms like headache or flushing often pass within a few hours. Back pain or muscle aches may last up to 48 hours. If side effects persist, contact your doctor.

Tips to Help Manage Side Effects

• Stay hydrated: Drinking water can help your body process the medicine
• Avoid spicy or greasy foods: These can make indigestion worse
• Keep cool: Stay in a cool environment if you feel hot or flushed
• Ask about antacids: These may help with stomach upset - check with your doctor first

Can You Eat Grapefruit While Taking Cialis?

Grapefruit and grapefruit juice are not recommended when taking Cialis. They can interfere with how your body breaks down tadalafil, increasing the risk of side effects.

Key Tip:

Avoid grapefruit products during treatment and for a few days after your last dose. If unsure, speak to your doctor or pharmacist.

Always read the leaflet provided with your medicine and consult a healthcare professional before starting Cialis to make sure it’s safe and suitable for you.

What should I know before taking Cialis (Tadalafil)?

Cialis is generally safe when used correctly, but there are some important precautions to keep in mind.

Do not take Cialis if:

• You are taking nitrate medicines (such as GTN spray or isosorbide mononitrate), often used for chest pain.
• You use recreational drugs like poppers (amyl nitrate).

Using Cialis with these substances can cause a dangerous drop in blood pressure, which may be life-threatening.

Is Cialis addictive?

Cialis is not physically addictive, meaning it doesn’t cause withdrawal symptoms if you stop taking it. However, some people may develop a psychological dependence if they rely on it for confidence or performance.

• No physical addiction: You won’t experience withdrawal if you stop taking it.
• Use as prescribed: Only take it when needed and as directed to avoid overuse or mental dependence.

How to take Cialis safely

• Always follow your doctor’s advice and prescription.
• Only use Cialis if it has been prescribed for you.
• Never share your medicine with others, even if their symptoms seem similar.
• If you’re unsure about anything, ask your doctor or pharmacist.

Taking Cialis the right way helps ensure it works effectively and reduces the risk of side effects. If you have any unusual symptoms or concerns, speak to a healthcare professional.

Here are answers to some of the most frequently asked questions about Cialis (tadalafil) from UK Meds customers.

Can I drink alcohol while taking Cialis?

Heavy drinking while taking the medication is not recommended. It’s best to limit or avoid alcohol when using Cialis. Both alcohol and Cialis can lower your blood pressure, combining them can lead to dangerous drops in blood pressure, headaches, dizziness and other heart problems. Limiting your alcohol consumption when taking Cialis maximize its effectiveness, according to NHS guidelines.

Always follow your doctor’s advice about alcohol use while taking this medicine.

Can I become dependent on Cialis?

No, Cialis is not physically addictive and won’t cause withdrawal symptoms if you stop taking it. However, some people may develop a psychological dependence, especially if they use it to manage performance anxiety or take it for non-medical reasons.

Relying on Cialis for confidence during sex can lead to overuse or feeling unable to perform without it. If you're concerned about this, speak to a healthcare professional for support and guidance.

Are there any medicines I shouldn’t take with Cialis?

Yes. Cialis (tadalafil) can interact with certain medicines, especially those that lower blood pressure. This includes prescription drugs, over-the-counter medicines, and recreational substances like "poppers". To stay safe, always tell your doctor or pharmacist about all medications, supplements, and herbal products you're using before starting Cialis.

Important: Do not take Cialis if you’re using:

• Nitrates (such as GTN spray or isosorbide mononitrate for chest pain)
• Poppers (amyl nitrate or similar recreational drugs)
• Riociguat (a treatment for high blood pressure in the lungs)
• Certain herbal supplements

Combining these with Cialis can lead to a dangerous drop in blood pressure. Always check with your GP or pharmacist before taking Cialis with any other treatment or supplement.

Is Cialis stronger than Viagra?

Not necessarily. Both treat erectile dysfunction, but differ in how long they last:

• Cialis: Works for up to 36 hours
• Viagra: Lasts about 4 to 6 hours

Cialis lasts longer, but one isn’t stronger than the other. Your doctor can help you choose the best option for your needs.

What else can Cialis be used for?

In addition to treating erectile dysfunction, Cialis (tadalafil) may also be prescribed for:

• Benign Prostatic Hyperplasia (BPH): Helps relieve urinary symptoms caused by an enlarged prostate, such as difficulty urinating or needing to go more often.
• Pulmonary Hypertension: Used to lower blood pressure in the lungs, helping the heart work more efficiently.

These uses require a prescription and should only be followed under the guidance of a healthcare professional.

Can Cialis treat premature ejaculation?

Cialis (tadalafil) is not licensed to treat premature ejaculation (PE). Its main use is for erectile dysfunction (ED). However, some studies suggest it may help delay ejaculation in men who experience both ED and PE (Karabakan et al, 2017). Results can vary and may not work the same for everyone (Abou Faddan et al, 2022).

If you’re concerned about premature ejaculation, speak to your doctor. They can recommend the most suitable treatment for your needs.

What other erectile dysfunction treatments are available?

If medicines like Cialis or Viagra aren’t right for you, there are other effective options to explore. These include therapy, lifestyle changes, and alternative ED treatments.

1. ED Counselling and Therapy

If stress, anxiety, or low sex drive is affecting your erections, talking to a professional may help.

• Therapy can support mental wellbeing and boost confidence in the bedroom.
• NHS counselling services may be available. Speak to your GP for more details.

2. Healthy Lifestyle Changes

Health issues like high blood pressure or heart disease can cause ED. Making small changes can help:

• Eat a healthy, balanced diet
• Exercise regularly
• Stop smoking and reduce alcohol intake

These habits can improve blood flow and support natural erections (Yannas et al., 2021).

3. Other ED Medications

If standard tablets aren’t suitable, there are other treatments that may help.

ED Creams

• Vitaros (Alprostadil) – a cream applied directly to the penis for fast results

Alternative Tablets

• Viagra (Sildenafil) or Viagra Connect
• Spedra (Avanafil)
• Levitra (Vardenafil)
• Cialis Daily or Cialis Together

How do I know which treatment is right for me?

Everyone’s needs are different. A GP or registered independent prescriber can help you find the safest and most effective option based on your health and lifestyle.

UK Meds is committed to providing you with the most accurate information possible regarding healthcare and lifestyle, as outlined in our Editorial Policy and Content Policy. We aim to regularly peer review and update our content as necessary to give you the most up-to-date medical information, helping you to be fully informed before starting a consultation with a registered prescriber for the treatment that you need.

Please note that our content is not a substitute for professional medical advice. Before starting any treatment or making any changes that could affect your lifestyle, you should always speak with your doctor, pharmacist or healthcare provider to ensure that it is safe and suitable for you.

1st July 2025

• NHS - Tadalafil
• Patient.info - Tadalafil for erectile dysfunction or enlarged prostate
• European Medicines Agency - Cialis
• Drugs.com - Cialis
• British National Formulary (BNF) - Tadalafil

• How to Get the Best Results from Cialis - Tips to maximise the effectiveness of Cialis for ED treatment.
• Cialis London: A Guide To Buying Cialis In The UK's Capital - A guide to buying Cialis in London
• Can I Get Cialis Without A Prescription? - A guide explaining over the counter options for tadalafil
• Cialis vs Viagra: Which Is Best? - Compare Cialis and Viagra to find the best option for your needs.
• Viagra vs Levitra vs Cialis - A detailed comparison of these three popular ED medications.
• Taking Erectile Dysfunction Medication with Alcohol - Learn if it’s safe to mix ED drugs like Cialis with alcohol.
• Can I Take ED Drugs After a Heart Attack? - Understand if it’s safe to use ED medications after a heart condition.
• Alternatives to Viagra - Explore other options beyond Viagra for treating ED.
• Erectile Dysfunction Medication - Explore available medications for managing erectile dysfunction.
• What Causes Erectile Dysfunction? - Learn about the common reasons behind erectile dysfunction.