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Cialis (Tadalafil)

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Cialis is an effective treatment for erectile dysfunction (ED), helping men regain confidence in their sex lives. It works by increasing blood flow to the penis during sexual arousal, making it easier to achieve and maintain a healthy erection. Backed by research (Ma et al., 2020, Gallo et al., 2020, Washington & Shindel, 2010), Cialis is trusted worldwide. Available in the UK through an online clinical consultation at UK Meds, prescriptions are issued by registered independent prescribers.

We also offer:
  • Cialis Daily: A version of Cialis tablets taken daily
  • Cialis Together: An over the counter version of Cialis (tadalafil), which doesn't require a prescription.
  • Lasts for 36 hours
  • Take 2 hours before sex
  • Allows for sexual spontaneity
  • Genuine medication
  • All drugs sourced in the UK
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A Doctor's Overview

Dr Shane Charles (MBBS, MRCS, PgDip SEM) - GMC Number 8085739

GP and surgeon, Dr Shane Charles (MBBS, MRCS, PgDip SEM) provides a simple explanation of the medication below:

'Cialis (Tadalafil) is used to manage male erectile dysfunction as well as benign prostatic hyperplasia (BPH). '.

If you think this is a treatment that can help you, start an online consultation now for a registered prescriber to review. If treatment is deemed suitable, they can prescribe it, and we can deliver it to you from the comfort of your own home with a range of convenient delivery and payment options for you to choose from. If you have any questions about a medication, you should always consult your doctor with any questions prior to starting treatment, to ensure that it is safe and suitable for you.

Buy Cialis Online

Where can I buy Cialis online in the UK?

Buy Tadalafil

You can buy Cialis or its generic version, Tadalafil, online in the UK through trusted services like UK Meds. If you already have a prescription, we’ll process your order straight away. If not, simply complete a quick and free online consultation. A registered independent prescriber will review your answers and, if approved, you can place your order online.

Can I get Cialis on subscription?

Yes, UK Meds offers a Cialis (Tadalafil) subscription service. This ensures your medication is delivered regularly, so you never run out. Subscriptions can also be more cost-effective than one-off orders.

Is it legal to buy Cialis online in the UK?

Yes, buying Cialis or Tadalafil online is legal in the UK, provided you have a valid prescription. At UK Meds, all medication is dispensed by UK-registered pharmacies and is 100% genuine. You’ll need to complete a free online consultation to confirm the treatment is suitable for you.

Can I get Cialis without a prescription?

Cialis Together – Over-the-Counter Option

Yes, you can get Cialis over-the-counter without a prescription under the brand name "Cialis Together". However, you will need to have a consultation with a prescriber first, who will ask you a few questions to ensure it's suitable for you.

It's intended for adult men with erectile dysfunction and works by helping to improve blood flow, making it easier to get and keep an erection during sex.

Can I buy Cialis in London?

Cialis London

Yes, you can order Cialis online in London from UK Meds. If you have a prescription, you can complete your purchase easily. If not, you can fill in a short consultation, which will be reviewed by a registered independent prescriber. Once approved, your treatment will be delivered discreetly to your door. Always consult a healthcare professional before starting new medication.

For more details, read our Cialis London guide.

Can I buy Cialis in Manchester?

Cialis Manchester

Yes, you can buy Cialis online in Manchester via UK Meds. Place an order using your existing prescription or complete our free online consultation. After review by a registered independent prescriber, your medication can be delivered directly to your address. Always seek advice from a healthcare provider before starting Cialis.

Read our Cialis Manchester guide for more information.

For detailed information about this prescription medicine, please read the Cialis (Tadalafil) patient information leaflet.

Cialis Reviews

What do users say about Cialis?

Cialis (tadalafil) is well-reviewed by many men who use it for erectile dysfunction (ED). Users often report feeling more confident and enjoying a better sex life.

  • Real experiences: Check reviews from UK Meds customers above to see how Cialis has helped others in the UK.
  • More reviews: You can also read user feedback on trusted sites like Drugs.com and WebMD.

Is Cialis right for you?

Cialis works differently for everyone. Some people notice results quickly, while others may need to try it a few times before it helps.

  1. Speak to your doctor: Always get medical advice first to make sure Cialis is safe and suitable for you.
  2. Listen to your body: Reviews are useful, but your personal experience is the most important.

Follow your healthcare provider’s instructions when starting any new medication.

Cialis - Key Information

What is Cialis (Tadalafil)?

Understanding Cialis and Tadalafil

Cialis is a popular treatment for erectile dysfunction (ED). It contains the active ingredient tadalafil.

  • Tadalafil helps men get and keep an erection during sexual activity.
  • It’s often called the "weekend pill" because it can work for up to 36 hours.
  • Tadalafil is the generic version of Cialis and is usually cheaper.

Before using Cialis or tadalafil, speak to your doctor or pharmacist to check if it’s right for you.

Is there a generic version of Cialis?

Yes. Tadalafil is the generic drug form of Cialis. Generic drugs are an exact copy of an active drug in a branded medication. Generic drugs are generally considered to be as safe and effective as the original drug and tend to be cheaper than brand-name version of the drugs. It's been available in the UK since 2017 when the Cialis patent expired.

  • Both contain the same active ingredient.
  • They work the same and have the same possible side effects.
  • The main difference is cost – tadalafil is more budget-friendly.

Tadalafil offers the same results at a lower price. A healthcare professional can help you decide which is best for you.

Cialis Options in the UK

You can buy the following at UK Meds:

If you don’t have a prescription, complete a free online consultation with a registered independent prescriber.

How does Cialis (Tadalafil) work?

Tadalafil, the active ingredient in Cialis tablets, works by relaxing blood vessels and increasing blood flow to the penis. It's main use is to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). For both health conditions, it inhibits an enzyme called phosphodiesterase type 5 (PDE5), which is responsible for constricting blood vessels and muscles (Fahmy & Hess, 2024; Coward & Carson, 2008).

  • Note: Cialis does not increase sexual desire. If you have low libido, speak to your doctor about other treatments.
  • Note: Cialis does not increase sexual desire. If you have low libido, speak to your doctor about other treatments.
  • How effective is Cialis?

    In clinical studies comparing Cialis to a placebo, participants saw significant improvements in their erectile function when taking Cialis and the other drugs in the same class. Whilst it is considered a safe and effective drug, it may not be an appropriate treatment for everyone and may not work as effectively for all patients.

    Cialis is effective for many men:

    • Over 80% of users report achieving a firm erection (Skoumal et al., 2004).
    • Its effects can last up to 36 hours, offering more flexibility.
    • You may need to try it 8 times before deciding if it works for you.
    • It usually works well for older men and those with diabetes, without needing a dose change.
    • It may not work as well for men who’ve had pelvic surgery or prostate removal.

    Cialis is a trusted option for treating ED. Speak with your doctor to see if it’s suitable for you.

    Usage Advice

    How do you take Cialis?

    Cialis (tadalafil) comes in four strengths: 2.5mg, 5mg, 10mg, and 20mg. The right dose depends on how often you want to take it.

    • Occasional use: Take 10mg or 20mg before planned sexual activity.
    • Daily use: Take 2.5mg or 5mg once a day for more flexibility and spontaneity.
    • Some men find that 5mg works well even when used occasionally.

    Tips for First-Time Users

    Cialis might not work straight away. Experts suggest trying it at least eight times before considering another option.

    How to Take Cialis:

    1. Take one tablet about 30 minutes before sex, unless you're on a daily dose.
    2. Sexual arousal is required – Cialis only works if you’re turned on.
    3. You can take it with or without food. Swallow the tablet whole with water.
    4. Do not use with other ED medications – avoid taking Cialis within 24 hours of any similar treatment.

    Follow the instructions from your doctor. If you’re unsure about your dose or how to take it, speak to a GP or pharmacist.

    How long does Cialis take to work?

    Cialis usually starts to work within 30 minutes, but only when you are sexually aroused.

    • The effects can last up to 36 hours, earning it the nickname "the weekend pill".

    How long should I take Cialis for?

    You can use Cialis for as long as your doctor advises. There are no known risks with long-term use.

    • Take it only when needed, or daily if prescribed.
    • Make sure to have regular check-ups to see if it’s still the best option for you.

    Dosage

    Cialis, also known as tadalafil, treats erectile dysfunction (ED). It comes in four strengths: 2.5mg, 5mg, 10mg, and 20mg. The right dose depends on how often you need it and your doctor’s advice.

    Cialis Dosage Options

    Cialis Daily (for regular use)

    • 2.5mg: A lower dose used if 5mg causes side effects.
    • 5mg: The usual daily dose, ideal if you have sex more than twice a week.

    Cialis as Needed (for occasional use)

    • 10mg: Common starting dose for one-off use.
    • 20mg: Used if 10mg isn’t effective and you don’t experience side effects.

    Cialis Dosage Guidelines

    36-Hour Cialis (occasional use)

    DoseHow to take
    10mg or 20mgStart with 10mg. If needed, increase to 20mg after checking with your doctor.

    Cialis Daily (everyday use)

    DoseHow to take
    2.5mg or 5mgStart with 5mg once a day. Your doctor may change the dose if needed.

    Cialis Together (non-prescription version)

    DoseHow to take
    10mgTake one tablet 30 minutes before sex.

    Key Points to Remember

    • Always follow your doctor’s instructions when taking Cialis or changing your dose.
    • Daily doses are best if you have sex more than twice a week.
    • As-needed doses are better for occasional use.
    • Your dose may be adjusted depending on how well it works or if you get side effects.

    Talk to your doctor or pharmacist to find the dose that suits you best.

    Side Effects

    What are the side effects of Cialis (Tadalafil)?

    Cialis is generally well-tolerated, but like all medicines, it can cause side effects. Most are mild and go away on their own.

    Common Side Effects

    These affect up to 1 in 10 people and usually pass quickly:

    • Headache
    • Indigestion or upset stomach
    • Blocked or stuffy nose
    • Muscle aches
    • Back pain

    If any of these symptoms persist or bother you, speak to your doctor or pharmacist.

    Serious (but Rare) Side Effects

    These are less common but may need urgent medical attention:

    • Chest pain
    • Fast or irregular heartbeat
    • Hearing loss or ringing in the ears
    • Very low or high blood pressure
    • Painful or prolonged erections lasting over 4 hours (called priapism)
    • Severe allergic reaction – rash, swelling, or trouble breathing

    What is priapism?

    Priapism is a rare condition where an erection lasts longer than 4 hours without appropriate sexual stimulation (Silberman et al, 2023). If this happens, seek emergency medical help to prevent lasting damage.

    How to Reduce Side Effects

    • Take the lowest dose your doctor recommends
    • Read the leaflet that comes with your tablets
    • Tell your doctor if any side effects are severe or long-lasting

    How long do Cialis side effects last?

    Mild side effects like headaches or flushing often settle within a few hours. Muscle aches or back pain can last up to 48 hours. If symptoms continue, speak to your doctor.

    Tips to Avoid Side Effects

    • Stay hydrated: Drink plenty of water to help your body process the medicine
    • Avoid spicy or greasy food: These may make indigestion worse
    • Keep cool: Use a fan or stay in a cool room if you feel hot or flushed
    • Ask about antacids: These may help with indigestion, but check with your doctor first

    Can I eat grapefruit while taking Cialis?

    No, consuming grapefruit or grapefruit juice while taking Cialis (tadalafil) is generally not recommended. Grapefruit can interfere with the enzymes in your liver and intestine that help your body to process Cialis, which can potentially increase blood levels of the drug, raising the risk of side effects.

    Key Tip:

    Avoid grapefruit products while taking Cialis and for a few days after your last dose. Ask your doctor or pharmacist if you're unsure.

    Always read the patient information leaflet and speak to your doctor before starting Cialis to ensure it’s safe for you.

    Warnings

    What should I know before taking Cialis (Tadalafil)?

    Cialis is generally safe when used properly, but there are some important precautions to follow to avoid risks.

    Do not take Cialis if:

    • You are using nitrate medications (like GTN spray or isosorbide mononitrate), which are often used for chest pain.
    • You use recreational drugs such as poppers (amyl nitrate).

    Combining these with Cialis can cause a dangerous drop in blood pressure, which may be life-threatening.

    Is Cialis addictive?

    No, generally, Cialis is not considered addictive in the traditional sense of physical dependence that lead to withdrawal symptoms. However, if a person feels they need it for sexual confidence or performance it can cause psychological dependence to develop.

    • No physical addiction: You won’t get withdrawal symptoms if you stop taking it.
    • Use it only when needed: Taking Cialis for non-medical reasons can lead to psychological dependence or side effects.

    How to take Cialis safely

    • Follow your doctor’s instructions carefully.
    • Only take Cialis if it has been prescribed for you.
    • Do not share your tablets with anyone else, even if they have similar symptoms.
    • If you’re unsure about anything, ask your doctor or pharmacist.

    Taking Cialis correctly helps it work safely and effectively. If you notice anything unusual or have concerns, speak to a healthcare professional.

    Cialis FAQs

    Here are answers to some of the most frequently asked questions about Cialis (tadalafil) from UK Meds customers.

    Can I drink alcohol while taking Cialis?

    Heavy drinking while taking the medication is not recommended. It’s best to limit or avoid alcohol when using Cialis. Both alcohol and Cialis can lower your blood pressure, combining them can lead to dangerous drops in blood pressure, headaches, dizziness and other heart problems. Limiting your alcohol consumption when taking Cialis maximize its effectiveness, according to NHS guidelines.

    Always follow your doctor’s advice about alcohol use while taking this medicine.

    Can I become dependent on Cialis?

    No, in the traditional sense Cialis is not considered an addictive drug but some individuals may develop a psychological dependence on it. This is especially problematic if Cialis is used to treat performance anxiety or for recreational purposes, where the individual can begin to rely on the medication when having sex, just to feel confident in their sexual performance.

    Are there any medicines I shouldn’t take with Cialis?

    Yes. Tadalafil, the active ingredient in Cialis, can interact with several medications, particularly medication that lower blood pressure, such as nitrates, certain blood pressure medications and recreational drugs like "poppers". You should always inform your doctor about all the medications and supplements you are currently taking before starting treatment with Cialis, to avoid experiencing any serious interactions between the treatments.

    Remember:

    You should not take Cialis if you are using:

    • Nitrates (e.g. GTN spray for chest pain)
    • Poppers (amyl nitrate)
    • Riociguat (used for high blood pressure in the lungs)
    • Some herbal supplements

    Taking Cialis with these can cause a dangerous drop in blood pressure. Always check with your GP or pharmacist before combining it with any other medicines or supplements.

    Is Cialis stronger than Viagra?

    Not necessarily. Both treat erectile dysfunction, but differ in how long they last:

    • Cialis: Works for up to 36 hours
    • Viagra: Lasts about 4 to 6 hours

    Cialis lasts longer, but one isn’t stronger than the other. Your doctor can help you choose the best option for your needs.

    What else can Cialis be used for?

    Aside from erectile dysfunction, Cialis may also be prescribed for:

    • Benign Prostatic Hyperplasia (BPH): Eases urinary symptoms linked to an enlarged prostate.
    • Pulmonary Hypertension: Helps lower blood pressure in the lungs to support heart function.

    Only take Cialis for these conditions if your doctor has prescribed it.

    Can Cialis treat premature ejaculation?

    While Cialis (tadalafil) is not licensed as a treatment for premature ejaculation and is primarily used to treat erectile dysfunction, some studies and clinical observations suggest it can help premature ejaculation (PE). Specifically, it may prolong the time it takes to ejaculate, potentially benefiting individuals experiencing both ED and PE (Karabakan et al, 2017), but this may not have the same effect for every patient (Abou Faddan et al, 2022).

    If this is a concern for you, speak to your doctor for suitable treatment options.

    Alternative ED Treatments

    What other erectile dysfunction treatments are available?

    If medicines like Cialis or Viagra aren’t suitable for you, there are other options to consider. These include counselling, lifestyle changes, and different ED treatments.

    1. ED Counselling and Therapy

    If stress, anxiety, or low sex drive are affecting your erections, talking to a professional can help.

    2. Healthy Lifestyle Changes

    Some physical conditions like high blood pressure or heart disease can lead to ED. Making healthier choices can help:

    • Eat a balanced diet
    • Exercise regularly
    • Quit smoking and cut down on alcohol

    These changes can improve blood flow and help improve your erections naturally (Yannas et al., 2021).

    3. Other ED Medications

    If standard ED tablets aren’t suitable, other effective options are available.

    ED Creams

    Other Tablets

    How do I know which treatment is right for me?

    Everyone is different. A GP or registered independent prescriber can help find the safest and most effective treatment based on your health and personal needs.

    Sources:

    Author

    Content author

    Scott Weaver

    Medical Content Writer • Bachelor of Arts Degree

    Scott is an experienced, skilled medical content writer dedicated to creating helpful and accessible medical content for UK Meds.

    Read more

    Medical Reviewer

    Medical Reviewer

    Alexis Missick

    General Practitioner (GP) • MBChB

    With over a decade of experience in the NHS and six years internationally, Alexis is a seasoned General Practitioner hailing from Turks and Caicos.

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