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NAD+ Injections

Support Your Cellular Health & Energy

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell of the body. It plays a key role in energy production, DNA repair and cellular communication. As we age, NAD+ levels naturally decline, which can impact overall health and contribute to ageing-related conditions. Maintaining optimal NAD+ levels through NAD+ therapy such as using NAD+ self-injections and supplements can support cellular regeneration, cognitive function, metabolic health, and overall well-being.

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Boost Your Wellness with Self-Injection NAD+ Pens

Support your energy, focus, and overall health with NAD+ self-injection pens.

NAD+ (Nicotinamide Adenine Dinucleotide) is a natural substance found in every cell of your body. It helps create energy, repair cells, and keep your brain and body working at their best. But as we age, NAD+ levels drop, which can lead to tiredness, brain fog, and slower recovery.

UK Meds makes it easy to feel your best. Our NAD+ pens are simple to use at home, giving you the flexibility to boost your wellbeing on your own schedule – without the need for a clinic visit.

If you're looking for a way to feel sharper, more energised, and support healthy ageing, NAD+ therapy could be the solution.

What Are NAD+ Injections?

NAD+ injections are a fast and efficient way to boost your body’s levels of Nicotinamide Adenine Dinucleotide (NAD+), a vital molecule that helps power your cells. These injections are popular in the fields of health optimisation, longevity, and anti-ageing [1][2].

By delivering NAD+ directly into your bloodstream, injectable treatments may support:

  • Improved energy production at the cellular level
  • Enhanced brain function and mental clarity
  • Support for healthy ageing and DNA repair
  • Faster recovery from stress, fatigue, or illness

Understanding NAD+ (Nicotinamide Adenine Dinucleotide)

NAD+ is a coenzyme found in every cell of your body [3][4]. It plays a key role in:

  • Converting food into usable energy (ATP)
  • Repairing damaged DNA and maintaining cell health
  • Supporting metabolism and mitochondrial function
  • Activating longevity-related proteins (sirtuins)

Without enough NAD+, your cells may struggle to perform basic functions—leading to fatigue, brain fog, and signs of premature ageing.

Why NAD+ Levels Decline With Age

As we get older, our natural NAD+ levels start to drop. This decline can be made worse by:

  • Stress and poor sleep
  • Excess alcohol or sugar consumption
  • Chronic illness or inflammation
  • Exposure to toxins and pollutants

This reduction in NAD+ has been linked to age-related health issues such as low energy, weakened immunity, poor memory, and reduced cellular repair [5][2].

What Makes Injectable NAD+ Different From Pills or Patches?

While NAD+ supplements come in various forms, such as capsules, patches, or oral treatments, injectables offer unique benefits in terms of speed and effectiveness.

FormAbsorptionOnset TimeTypical Use
NAD+ InjectionsHigh – it goes directly into bloodstreamFast – often within hoursTargeted energy boost, brain support, anti-ageing
NAD+ PillsLow to moderate – can be affected by digestionSlower – may take weeks to notice effectsGeneral daily support
NAD+ PatchesModerate – absorbed through skinModerate – gradual releaseConvenient but less potent than injections

NAD+ injections are often chosen by people who want noticeable results quickly, especially if they are feeling run-down, have demanding lifestyles, or are actively pursuing wellness and longevity goals.

How Do NAD+ Injections Work in the Body?

NAD+ injections deliver this essential coenzyme straight into your bloodstream, where it can quickly get to work supporting your cells. Unlike oral supplements, which must pass through the digestive tract, injections allow NAD+ to be absorbed directly and efficiently.

The Role of NAD+ in Cellular Energy (ATP) Production

Every cell in your body relies on NAD+ to generate energy. It does this by helping your mitochondria (the powerhouses of your cells) convert nutrients into ATP, your body’s main energy currency1.

Without enough NAD+, your cells may struggle to:

  • Maintain normal energy levels
  • Carry out vital functions such as repair and regeneration
  • Combat oxidative stress and inflammation

This is why NAD+ therapy is often associated with improved energy, clearer thinking, and better overall vitality [6].

How Injecting NAD+ Bypasses the Digestive System

When taken by mouth, NAD+ must be broken down by the digestive system and absorbed through the gut. This process can reduce how much of the active ingredient actually makes it into your bloodstream.

With injections, NAD+ bypasses the digestive system entirely and enters the bloodstream directly. This offers several key benefits:

  • Higher absorption and bioavailability
  • Faster onset of effects – often within hours
  • More predictable and consistent results

This makes injectable NAD+ ideal for people who need quick, noticeable support, whether for brain fog, fatigue, stress, or active recovery.

Scientific Evidence Supporting NAD+ Therapy

Research into NAD+ therapy is growing, with studies highlighting its potential to support various aspects of health and ageing:

  • Energy metabolism: Studies show that NAD+ is vital for mitochondrial function and ATP production, directly influencing how energised you feel[1].
  • Brain function: NAD+ may support cognitive performance and protect neurons against age-related damage [7].
  • Cell repair: NAD+ activates sirtuins, a group of proteins that help repair DNA and regulate ageing [8].
  • Anti-ageing benefits: Animal studies have linked higher NAD+ levels with improved lifespan and delayed age-related decline [9].

What is NAD+ Therapy?

NAD+ (Nicotinamide Adenine Dinucleotide) is a natural substance found in every cell of your body. It helps turn food into energy, supports cell repair, and keeps your brain and body working properly.

As you get older, your NAD+ levels drop. This can lead to tiredness, brain fog, slower recovery from exercise, and feeling generally run down. NAD+ therapy helps top up these levels, giving your body the support it needs to function at its best.

By restoring NAD+, you may feel more energised, focused, and refreshed – all while supporting healthy ageing and long-term wellbeing.

Who Can Benefit from NAD+ Therapy?

NAD+ therapy may be helpful if you:

  • Often feel tired or low on energy
  • Struggle with focus or mental clarity
  • Recover slowly after stress, illness, or physical activity
  • Want to support your overall wellness and healthy ageing

If you're not sure whether NAD+ is right for you, our team is here to help you decide based on your individual health needs and goals.

NAD+ Injections vs Other NAD+ Supplements

If you're looking to boost your NAD+ levels, you may be wondering which method is best: injections, capsules, precursors like NMN or NR, or even IV drips. Each option has its pros and cons depending on your goals, lifestyle, and budget. Here's a breakdown to help you decide.

Injections vs NAD+ Oral Capsules

Oral capsules are one of the most widely available forms of NAD+ supplementation, but they may not offer the same level of effectiveness as injections.

FeatureNAD+ InjectionsNAD+ Capsules
AbsorptionHigh – enters bloodstream directlyLow to moderate – depends on gut health
Speed of EffectFast – often noticeable within hoursSlower – may take weeks of consistent use
BioavailabilityVery highReduced due to digestive breakdown
ConvenienceRequires administration (self-injection or clinic)Simple – just swallow daily

While capsules may suit those looking for convenience, injections could be better for people wanting fast, noticeable results. As always, results may vary.

NAD+ Injections vs NMN and NR (Precursors)

NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside) are popular supplement ingredients known as NAD+ precursors. This means they need to be converted by the body into NAD+.

  • NMN/NR: Must go through a multi-step conversion process in the body, which may vary in efficiency depending on age and health.
  • NAD+ Injections: Provide NAD+ in its final active form, with no need for conversion.

While NMN and NR can be useful for general maintenance, injections may be more effective when a faster or stronger response is desired. For example, during times of high stress, fatigue, or ageing-related decline.

Injections vs IV Drips – What’s the Difference?

Both methods deliver NAD+ directly into the bloodstream, but the main difference is how they’re administered:

  • IV Drips: Usually take 1–2 hours and require a clinic visit.
  • Injections: Can be administered quickly at home in just a few minutes.

IV therapy is often used for high-dose or ongoing treatment protocols under supervision. Injections, meanwhile, offer a more flexible and time efficient option with similar potential benefits.

Which Option Is Right for Me?

The best NAD+ supplement for you depends on your goals, preferences, and health status. Here’s a quick guide:

GoalBest Option
Quick energy and brain boostNAD+ Injections
General wellness or maintenanceNAD+ Capsules or NR/NMN
Ongoing or high-dose therapyIV Drip (clinic-based)
Long-term anti-ageing supportInjections or NMN (depending on preference)

If you're unsure which form is best, consider speaking with a registered healthcare professional or undergoing a clinical consultation. Everyone’s needs are different, and what works best for one person may not be ideal for another.

Lifestyle Tips to Naturally Support NAD+ Levels

While NAD+ injections can offer a fast and effective boost, your daily habits also play a powerful role in preserving and supporting your body’s natural NAD+ production. Making small but consistent changes to your lifestyle may help maintain long-term cellular health and slow the natural decline in NAD+ levels that occurs with age.

Diet and Foods That May Help Boost NAD+

Eating a balanced diet rich in vitamin B can support NAD+ synthesis in the body. Nutrients like niacin (vitamin B3) and tryptophan are precursors your cells use to produce NAD+ [12].

Foods that may support NAD+ production:

  • Avocados – rich in B vitamins and healthy fats
  • Oily fish (e.g. salmon, mackerel, sardines) – provide B vitamins and support mitochondrial health
  • Dairy products like yoghurt and cheese – contain both niacin and tryptophan
  • Leafy greens – including spinach and kale, for antioxidant support
  • Whole foods over processed grains – minimise refined carbs which may contribute to inflammation

Hydration and avoiding excess sugar, alcohol, and processed foods can further help protect NAD+ levels and overall metabolic function.

Exercise and Sleep for Cellular Health

Regular movement and rest are crucial to keeping your mitochondria and NAD+ functioning efficiently [13][14][15][16]. Exercise increases NAD+ turnover, helping your body make better use of it.

  • Aerobic exercise: Running, walking, swimming, or cycling can stimulate mitochondrial activity and NAD+ production
  • Strength training: Helps regulate blood sugar and reduce oxidative stress
  • Sleep: Deep rest supports DNA repair and hormonal balance, both of which depend on NAD+-powered enzymes

Aim for at least 150 minutes of moderate activity per week and 7–9 hours of good-quality sleep each night, as advised by the NHS.

Reducing Stress to Protect NAD+ Reserves

Chronic stress can deplete NAD+ through increased inflammation and oxidative stress. Supporting your nervous system may help slow NAD+ breakdown and improve your sense of wellbeing.

Tips to help reduce stress [17][18]:

  • Practice mindfulness or breathing exercises
  • Get enough sleep 
  • Spend time outdoors or engage in creative hobbies and exercise.
  • Limit stimulants such as caffeine and alcohol
  • Use saunas or hot tubs, which may help stimulate NAD+ production through mild thermal stress
  • Maintain regular social interaction and emotional connection

Supplementation as an Additional Option

In addition to lifestyle changes, many people choose to support their NAD+ levels through supplementation. NAD+ injections and IV therapy are popular options that deliver NAD+ directly into the bloodstream for quick and efficient results.

These methods may complement your health goals, particularly during periods of high stress, low energy, or recovery. Lifestyle improvements and supplementation together may offer a more comprehensive approach to long-term vitality.

What Is a NAD+ Supplement?

A NAD+ supplement is a product designed to help restore the body's natural levels of Nicotinamide Adenine Dinucleotide (NAD+), a vital molecule found in every cell. As we age, our NAD+ levels naturally decline, which can affect metabolism, energy, brain function, and cellular repair.

NAD+ supplements aim to counteract this decline by replenishing the body’s supply. They come in various forms including oral capsules, precursors (like NMN or NR), patches, IV drips, and injections. Among these, NAD+ injections are considered one of the most effective methods, offering high bioavailability and rapid absorption by delivering NAD+ directly into the bloodstream.

As with all supplements, results may vary based on age, lifestyle, and individual health.

How to Take NAD+ Injections Safely

Using NAD+ injections safely is essential for getting the most benefit and avoiding unnecessary side effects. The NAD+ injection pen is designed for easy self-administration at home. Below is a complete guide on how to set up, inject, and store your NAD+ safely and effectively.

Self-Injecting at Home: What to Know

The NAD+ pen delivers the solution subcutaneously (under the skin). Each injection is controlled and easy to administer following a few simple steps. For best results and safety:

  • Start by injecting daily for the first three days
  • After this loading phase, inject every other day as needed
  • The recommended dose is up to 50mg per injection, equal to 30 units on the pen (0.3ml)

How to Set Up Your NAD+ Injection Pen

Before you begin, allow the pen and cartridge to reach room temperature (2–3 minutes). Then follow these steps:

  1. Remove the pen and cartridge from their packaging
  2. Take the lid off the pen and unscrew the cartridge holder
  3. If visible, gently push the plunger into the base of the pen
  4. Insert the NAD+ cartridge into the cartridge holder
  5. Screw the cartridge holder back into the pen
  6. Twist the pen until the dosage meter is fully exposed
  7. Push the dosage meter repeatedly until the plunger reaches the bottom of the cartridge and resistance is felt

Your pen is now primed and ready for injection.

How to Administer the Injection

Follow these steps for safe and effective self-injection:

  1. Screw a 6mm needle onto the pen and keep the needle tip cover on
  2. Clean your chosen injection site (stomach, thigh, or buttock) with an alcohol wipe
  3. Remove the needle tip cover
  4. Twist the dosage meter to select your desired dose (e.g. 30 units = 50mg)
  5. Pinch the skin to pull it away from the muscle
  6. Insert the needle subcutaneously and avoid movement to prevent bruising
  7. Press the button on the pen to deliver the dose
  8. Count to three before removing the needle
  9. Replace the needle cap and unscrew the needle from the pen
  10. Put the pen lid back on and store it in the fridge
  11. Dispose of the used needle in a sharps bin

To prevent irritation, rotate injection sites each time you inject.

Common Reactions and What to Expect

Mild, localised side effects are common and not usually cause for concern:

  • Redness or a small drop of blood at the injection site
  • A droplet of NAD+ solution on the skin after injection
  • Minor bruising if the needle moves during administration

If you experience persistent or severe symptoms, stop use and speak with a healthcare professional.

How Often Should You Take NAD+ Injections?

Injection frequency depends on your personal goals and wellness routine. General guidance includes:

  • Loading phase: 3 consecutive days of injections
  • Maintenance phase: Every other day (or as desired)

Each dose should not exceed 50mg (0.3ml). Always follow the usage instructions provided with your kit.

Best Practices for Storing and Administering NAD+

To maintain effectiveness and prevent spoilage:

  • Store the entire kit in a fridge between 2°C and 8°C
  • Allow the pen to reach room temperature before use
  • Keep the kit away from sunlight, heat, and moisture
  • Store safely out of reach of children and pets

Check vials before use for expiry, discolouration, or particles. Do not inject if the solution appears compromised.

How to Refill Your NAD+ Pen

  1. Remove the pen lid and unscrew the clear section
  2. Push the plunger down to reset it
  3. Remove the used cartridge and dispose of it in a sharps bin
  4. Insert a new NAD+ cartridge into the clear section
  5. Reattach the cartridge section to the pen and use as normal

When to Seek Medical Advice

It is highly recommended to consult a healthcare professional before taking NAD+ daily to ensure the appropriate dosage and frequency based on your health needs and goals[10].

Additionally, while NAD+ injections are generally well tolerated, you should speak to a healthcare professional if you experience:

  • Persistent swelling, redness, or pain at the injection site
  • Signs of allergy – rash, itching, or breathing difficulty
  • Unusual fatigue, headaches, or digestive upset
  • Any symptoms that concern you or feel unusual

What's Included in the NAD+ Pen Kit?

Your injection kit includes everything needed for safe home use:

  • 1x NAD+ self-injection pen
  • 2x NAD+ solution cartridges
  • Micro-needles (6mm)
  • Antibacterial wipes
  • 1x Sharps bin for safe disposal

Side Effects: Are NAD+ Injections Safe?

NAD+ injections are generally well tolerated when used correctly and may offer several wellness benefits. Because NAD+ is a coenzyme already found in the body, supplementing it through injections is considered low risk for most healthy adults. However, as with any supplement, it's important to understand the potential side effects, interactions, and when NAD+ may not be appropriate.

Possible Side Effects and How to Manage Them

Most side effects from NAD+ injections are mild and short-term. They are typically related to the injection process rather than the NAD+ compound itself.

  • Redness or swelling: Common at the injection site; usually fades within hours.
  • Bruising: May occur if the needle is moved or the same site is reused frequently.
  • Stinging or discomfort: Often reduced by letting the solution reach room temperature before injecting.
  • Fatigue or flushing: Can occasionally occur after first-time use but generally settles quickly.

How to reduce side effects:

  • Clean the injection site with an alcohol wipe before each use
  • Rotate between injection sites to avoid skin irritation
  • Inject slowly and stay still during administration
  • Warm the pen to room temperature before injecting

If symptoms are persistent, unusual, or severe, stop using NAD+ and consult a healthcare professional.

Who Should Avoid NAD+ Injections?

While NAD+ is safe for many people, it may not be suitable in certain circumstances. You should avoid or delay use if you:

  • Are pregnant or breastfeeding
  • Have an active or recent cancer diagnosis
  • Are receiving chemotherapy or immunosuppressive therapy
  • Have known allergies to any component in the injection

Does NAD+ Cause Cancer?

There is no clear evidence that NAD+ directly causes cancer. However, NAD+ plays a role in both cellular repair and energy production pathways. This includes glycolysis, which cancer cells use for rapid growth. Some research suggests cancer cells may exploit NAD+ metabolism to support tumour progression.

At the same time, NAD+ is essential for DNA repair and has even been studied as a potential support in cancer treatment [11]. The relationship between NAD+ and cancer is complex and not fully understood. If you have a history of cancer or are at increased risk, consult a healthcare professional before starting NAD+ supplementation.

Combining NAD+ With Other Wellness Supplements

NAD+ injections can be used alongside other supplements as part of a holistic wellness routine. Common combinations include:

  • Vitamin B12: Often paired with NAD+ to support energy and cognitive function
  • Magnesium: Helps with muscle recovery and relaxation
  • NMN or NR: NAD+ precursors that may support long-term NAD+ levels
  • Adaptogens: Such as rhodiola or ashwagandha, for stress resilience

Does NAD+ Interact With Medications?

NAD+ may interact with certain medications or change how the body responds to them. For example:

  • Some antidepressants may affect NAD+ availability, potentially making supplementation less effective
  • NAD+ may influence insulin sensitivity, which could affect people managing diabetes
  • Other anti-ageing supplements may enhance the effects of NAD+, possibly requiring dosage adjustments

If you are taking prescription medication or other supplements, it's best to speak to a healthcare professional before adding NAD+ to your daily routine. This helps ensure there are no unwanted interactions.

NAD+ FAQs

Below, UK Meds has answered some of the most common questions that our customers ask us about NAD+ supplementation:

What Does NAD Mean In Medical Terms?

In medical terms, NAD stands for nicotinamide adenine dinucleotide. This is a coenzyme that is present in the human body. It exists in two forms: NAD+ (oxidised) and NADH (reduced), both of which play key roles in processes like energy production, DNA repair and cellular communication. As we age, NAD+ levels naturally decline, contributing to various health issues and age-related diseases.

It is important to note that NAD+ differs from the abbreviation "NAD", commonly used on NHS health records. This stands for "Nothing Abnormal Detected" [19].

Do NAD+ injections hurt?

The pain associated with NAD+ injections is typically minimal. You may feel a slight pinch or discomfort when the needle is inserted. Allowing the NAD+ solution to reach room temperature before you inject it can help reduce discomfort. Rotating injection sites can also prevent irritation and soreness.

Is NAD B3?

NAD+ is closely related to vitamin B3 as it is derived from certain forms of this vitamin. There are three naturally occurring forms of vitamin B3: nicotinic acid, nicotinamide and nicotinamide riboside. These play a crucial role in maintaining adequate NAD+ levels in the body. While NAD+ itself is not the same as vitamin B3, the conversion of these B3 forms into NAD+ is essential for cellular health, energy production and various metabolic processes.

Can NAD+ affect hair growth?

Yes, research suggests that an increase in NAD+ levels, through NMN supplementation (a precursor of NAD), can promote hair follicle health, potentially improving hair growth and thickness. NAD+ is important in cellular processes such as DNA repair, energy production and oxidative stress response.

Buy NAD+ Injections Online from UK Meds

Can I buy NAD+ Injections online in the UK?

Yes, you can purchase NAD+ injections such as NAD+ injections by Vivere from UK Meds. Always consult your healthcare provider or doctor before taking NAD supplements to ensure they are safe and suitable for your individual needs.

Do I need a prescription?

No, currently NAD+ does not require a prescription to purchase, meaning it is available over the counter. You should still always consult a medical professional before starting any supplements or treatments.

Which NAD+ injections are available at UK Meds?

UK Meds currently offer the NAD+ injection by Vivere. Vivere’s NAD+ pen is the only one made in a trusted UK MHRA-licensed, GMP-certified facility and supplied by an NHS-approved, UKAS-certified partner.

Learn more with UK Meds support resources for NAD+:

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Author

Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled medical content writer dedicated to creating helpful and accessible medical content for UK Meds.

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