Can You Take NAD with GLP-1 Weight Loss Treatments Like Mounjaro?

As weight loss treatments become more advanced, many people are asking if they can combine different therapies for better results. One common question is: Can you take NAD with Mounjaro or other GLP-1 weight loss injections? Learn what NAD is, how it works and whether it’s safe or helpful to use alongside GLP-1 medications like Mounjaro with UK Meds below.

Key Takeaways

• NAD (nicotinamide adenine dinucleotide) is a natural compound that plays a role in energy production and metabolism.

• Mounjaro is a GLP-1 weight loss injection used to help people manage blood sugar and support weight loss.

• There is currently limited research on combining NAD with GLP-1 medications, but early data suggests it may be safe when taken responsibly.

• Always speak to a healthcare professional before combining treatments.

What Is NAD?

NAD, short for nicotinamide adenine dinucleotide, is a coenzyme found in all living cells. It plays a key role in how our bodies turn food into energy. NAD levels can decline as we age, which is why it’s often promoted for its anti-ageing and energy-boosting benefits.

Some people use NAD supplements or IV therapy as part of a wellness or weight loss routine. It’s believed to help improve metabolism, boost energy and support fat breakdown, although scientific evidence is still developing.

What Is Mounjaro?

Mounjaro (tirzepatide) is a once-weekly injection used to treat type 2 diabetes and support weight loss. It works by mimicking the effects of a hormone called GLP-1, which helps control blood sugar and reduce appetite.

It has become popular as part of medical weight management programmes, especially for those who struggle with traditional diet and exercise alone.

Can You Take NAD with Mounjaro?

If you're wondering if you can take NAD with Mounjaro, the answer is: possibly, but with caution.

There is no strong evidence to suggest that NAD negatively interacts with GLP-1 medications like Mounjaro. That said, because both treatments affect metabolism, it’s important to monitor how your body responds.

Some early reports suggest that NAD may support energy levels and fat metabolism [1] [2], which could potentially complement the appetite-reducing effects of GLP-1s. But because everyone’s body is different, combining the two may not work the same way for all.

Is NAD Safe to Use for Weight Loss?

NAD supplements and infusions are generally considered safe when used appropriately, although side effects can include [3] [4]:

• Nausea

• Headache

• Fatigue

• Digestive discomfort

It’s also worth noting that NAD is not licensed in the UK specifically for weight loss. Much of the evidence for NAD’s role in weight management is still theoretical or based on small studies.

If you're considering NAD for weight loss, especially alongside a medication like Mounjaro, it’s best to seek medical advice.

Should You Combine NAD and GLP-1s Like Mounjaro?

Combining NAD with GLP-1 medications might offer complementary benefits, such as:

• Improved energy levels

• Better fat metabolism

• Enhanced support during weight loss efforts

However, the potential risks or interactions are still not fully understood. You should never start or mix treatments without first speaking to a qualified healthcare provider.

At UK Meds, all prescription-only treatments are supplied only after an online consultation with a registered prescriber, who will decide if a treatment is suitable for you.

Final Thoughts

There is growing interest in combining NAD with GLP-1 weight loss treatments like Mounjaro. While there is no clear evidence to suggest harm, there is also limited clinical research to fully support the combination.

If you’re exploring multiple approaches to weight loss, the safest route is to work with a medical professional who can guide your plan based on your personal health needs. Always prioritise safety and evidence over trends.

Need Support with Weight Loss Treatments?

At UK Meds, we offer access to prescription weight loss medications, including GLP-1 injections, subject to an online consultation. All requests are reviewed by a registered prescriber who will decide if the treatment is right for you.

We also offer NAD+ injections, which may support energy and metabolism as part of a wellness routine. If you're considering NAD shots alongside a GLP-1 medication, speak to a healthcare professional to make sure it’s suitable for your needs.

Sources

[1] Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metab. 2018 Mar 6;27(3):529-547. doi: 10.1016/j.cmet.2018.02.011. PMID: 29514064; PMCID: PMC6342515.

[2] Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141. doi: 10.1038/s41580-020-00313-x. Epub 2020 Dec 22. PMID: 33353981; PMCID: PMC7963035.

[3] Hwang ES, Song SB. Possible Adverse Effects of High-Dose Nicotinamide: Mechanisms and Safety Assessment. Biomolecules. 2020 Apr 29;10(5):687. doi: 10.3390/biom10050687. PMID: 32365524; PMCID: PMC7277745.

[4] Qin Song, Xiaofeng Zhou, Kexin Xu, Sishi Liu, Xinqiang Zhu, Jun Yang, The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update, Advances in Nutrition, Volume 14, Issue 6, 2023, Pages 1416-1435, ISSN 2161-8313, https://doi.org/10.1016/j.advnut.2023.08.008.